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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Type-1 angiotensin II receptor
Species	Bos taurus (Bovine)
Gene	AGTR1
Synonym	Angiotensin II type-1 receptor AT1
Disease	N/A for non-human GPCRs
Length	359
Amino acid sequence	MILNSSTEDGIKRIQDDCPKAGRHNYIFIMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPTIIHRNVFFIENTNITVCAFHYESQNSTLPVGLGLTKNILGFLFPFLIILTSYTLIWKTLKKAYEIQKNKPRKDDIFKIILAIVLFFFFSWVPHQIFTFMDVLIQLGLIRDCKIEDIVDTAMPITICLAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSENGNSSTKKPAPCIEVE
UniProt	P25104
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3374
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL265681
Molecular formula	C48H68N12O11
IUPAC name	(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-(3-hydroxypropanoylamino)pentanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
Molecular weight	989.145
Hydrogen bond acceptor	13
Hydrogen bond donor	12
XlogP	0.9
Synonyms	BDBM50422229
Inchi Key	FKZWZKJTYJYJHQ-AOEIQLFRSA-N
Inchi ID	InChI=1S/C48H68N12O11/c1-27(2)39(58-41(64)33(54-38(63)18-21-61)12-8-19-52-48(49)50)44(67)55-34(22-30-14-16-32(62)17-15-30)42(65)59-40(28(3)4)45(68)56-35(24-31-25-51-26-53-31)46(69)60-20-9-13-37(60)43(66)57-36(47(70)71)23-29-10-6-5-7-11-29/h5-7,10-11,14-17,25-28,33-37,39-40,61-62H,8-9,12-13,18-24H2,1-4H3,(H,51,53)(H,54,63)(H,55,67)(H,56,68)(H,57,66)(H,58,64)(H,59,65)(H,70,71)(H4,49,50,52)/t33-,34-,35-,36-,37-,39-,40-/m0/s1
PubChem CID	10629796
ChEMBL	CHEMBL265681
IUPHAR	N/A
BindingDB	50422229
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
Kd	104.71 nM	PMID9379447	ChEMBL
Kd	105.0 nM	PMID9379447	BindingDB
RA	5.53 -	PMID9379447	ChEMBL

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