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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Adenosine receptor A1
Species	Rattus norvegicus (Rat)
Gene	Adora1
Synonym	A1 receptor A1-AR A1R adenosine receptor A1 RDC7
Disease	N/A for non-human GPCRs
Length	326
Amino acid sequence	MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
UniProt	P25099
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL318
IUPHAR	18
DrugBank	N/A

Ligand

Name	CHEMBL286479
Molecular formula	C17H12BrN3O2
IUPAC name	1-(3-aminophenyl)-6-bromo-3-methylchromeno[2,3-c]pyrazol-4-one
Molecular weight	370.206
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	3.7
Synonyms	BDBM50034373 1-(3-Amino-phenyl)-6-bromo-3-methyl-1H-chromeno[2,3-c]pyrazol-4-one
Inchi Key	AJNVTICMXDXXMW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H12BrN3O2/c1-9-15-16(22)13-7-10(18)5-6-14(13)23-17(15)21(20-9)12-4-2-3-11(19)8-12/h2-8H,19H2,1H3
PubChem CID	10090517
ChEMBL	CHEMBL286479
IUPHAR	N/A
BindingDB	50034373
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	780.0 nM	PMID7731018	ChEMBL
Ki	780.0 nM	PMID7731018	BindingDB

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