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Name | D(2) dopamine receptor |
---|---|
Species | Bos taurus (Bovine) |
Gene | DRD2 |
Synonym | Dopamine D2 receptor |
Disease | N/A for non-human GPCRs |
Length | 444 |
Amino acid sequence | MDPLNLSWYDDDPESRNWSRPFNGSEGKADRPPYNYYAMLLTLLIFVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPMLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRANLKAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKTVNPKIAKIFEIQSMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC |
UniProt | P20288 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL3998 |
IUPHAR | N/A |
DrugBank | N/A |
Name | CHEMBL432676 |
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Molecular formula | C10H12FNO2 |
IUPAC name | 7-amino-1-fluoro-5,6,7,8-tetrahydronaphthalene-2,3-diol |
Molecular weight | 197.209 |
Hydrogen bond acceptor | 4 |
Hydrogen bond donor | 3 |
XlogP | 1.1 |
Synonyms | 2,3-Naphthalenediol, 7-amino-1-fluoro-5,6,7,8-tetrahydro- SCHEMBL10619702 103347-60-0 |
Inchi Key | DTGQQBGSYWRGOX-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C10H12FNO2/c11-9-7-4-6(12)2-1-5(7)3-8(13)10(9)14/h3,6,13-14H,1-2,4,12H2 |
PubChem CID | 13662814 |
ChEMBL | CHEMBL432676 |
IUPHAR | N/A |
BindingDB | N/A |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand satisfies Lipinski's rule of five. |
Parameter | Value | Reference | Database source |
---|---|---|---|
K Bind | 1.27 uM | PMID2875183 | ChEMBL |
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