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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Histamine H4 receptor
Species	Mus musculus (Mouse)
Gene	Hrh4
Synonym	GPCR105 H4 receptor H4R HH4R
Disease	N/A for non-human GPCRs
Length	391
Amino acid sequence	MSESNSTGILPPAAQVPLAFLMSSFAFAIMVGNAVVILAFVVDRNLRHRSNYFFLNLAISDFLVGLISIPLYIPHVLFNWNFGSGICMFWLITDYLLCTASVYNIVLISYDRYQSVSNAVSYRAQHTGIMKIVAQMVAVWILAFLVNGPMILASDSWKNSTNTKDCEPGFVTEWYILTITMLLEFLLPVISVAYFNVQIYWSLWKRRALSRCPSHAGFSTTSSSASGHLHRAGVACRTSNPGLKESAASRHSESPRRKSSILVSLRTHMNSSITAFKVGSFWRSESAALRQREYAELLRGRKLARSLAILLSAFAICWAPYCLFTIVLSTYPRTERPKSVWYSIAFWLQWFNSFVNPFLYPLCHRRFQKAFWKILCVTKQPALSQNQSVSS
UniProt	Q91ZY2
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5657
IUPHAR	265
DrugBank	N/A

Ligand

Name	CHEMBL1632414
Molecular formula	C14H17ClN4O
IUPAC name	(NZ)-N-[(6-chloro-1H-benzimidazol-2-yl)-(1-methylpiperidin-4-yl)methylidene]hydroxylamine
Molecular weight	292.767
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	2.9
Synonyms	N/A
Inchi Key	ZKDRIYJOVIMHFC-AQTBWJFISA-N
Inchi ID	InChI=1S/C14H17ClN4O/c1-19-6-4-9(5-7-19)13(18-20)14-16-11-3-2-10(15)8-12(11)17-14/h2-3,8-9,20H,4-7H2,1H3,(H,16,17)/b18-13-
PubChem CID	136192874
ChEMBL	CHEMBL1632414
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
EC50	63.1 nM	PMID21044842	ChEMBL
Intrinsic activity	1.0 -	PMID21044842	ChEMBL
Ki	7.943 nM	PMID21044842	ChEMBL

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