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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	D(1) dopamine receptor
Species	Carassius auratus (Goldfish)
Gene
Synonym	Dopamine D1 receptor
Disease	N/A for non-human GPCRs
Length	363
Amino acid sequence	MAVLDLNLTTVIDSGFMESDRSVRVLTGCFLSVLILSTLLGNTLVCAAVTKFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVTEVAGFWPFGAFCDIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPRVAFVMISGAWTLSVLISFIPVQLKWHKAQPIGFLEVNASRRDLPTDNCDSSLNRTYAISSSLISFYIPVAIMIVTYTQIYRIAQKQIRRISALERAAESAQIRHDSMGSGSNMDLESSFKLSFKRETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCKRTSNGLPCISPTTFDVFVWFGWANSSLNPIIYAFNADFRRAFAILLGCQRLCPGSISMETPSLNKN
UniProt	P35406
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2368
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL541838
Molecular formula	C16H17NO2
IUPAC name	(1R,3S)-1-(aminomethyl)-3-phenyl-3,4-dihydro-1H-isochromen-5-ol
Molecular weight	255.317
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	1.9
Synonyms	CHEMBL1190906 (1R)-1alpha-(Aminomethyl)-3,4-dihydro-3alpha-phenyl-1H-2-benzopyran-5-ol BDBM50008828 SCHEMBL9802747 1-Aminomethyl-3-phenyl-isochroman-5-ol; hydrochloride
Inchi Key	UYGVYUSBNCJHOS-HOTGVXAUSA-N
Inchi ID	InChI=1S/C16H17NO2/c17-10-16-12-7-4-8-14(18)13(12)9-15(19-16)11-5-2-1-3-6-11/h1-8,15-16,18H,9-10,17H2/t15-,16-/m0/s1
PubChem CID	15711865
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50008828
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	53.0 nM	PMID1833546	BindingDB

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