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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	D(1) dopamine receptor
Species	Carassius auratus (Goldfish)
Gene
Synonym	Dopamine D1 receptor
Disease	N/A for non-human GPCRs
Length	363
Amino acid sequence	MAVLDLNLTTVIDSGFMESDRSVRVLTGCFLSVLILSTLLGNTLVCAAVTKFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVTEVAGFWPFGAFCDIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPRVAFVMISGAWTLSVLISFIPVQLKWHKAQPIGFLEVNASRRDLPTDNCDSSLNRTYAISSSLISFYIPVAIMIVTYTQIYRIAQKQIRRISALERAAESAQIRHDSMGSGSNMDLESSFKLSFKRETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCKRTSNGLPCISPTTFDVFVWFGWANSSLNPIIYAFNADFRRAFAILLGCQRLCPGSISMETPSLNKN
UniProt	P35406
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2368
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL555619
Molecular formula	C17H19NO3
IUPAC name	(1R,3S)-1-(aminomethyl)-6-methoxy-3-phenyl-3,4-dihydro-1H-isochromen-5-ol
Molecular weight	285.343
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	1.8
Synonyms	SCHEMBL9802704 1-Aminomethyl-6-methoxy-3-phenyl-isochroman-5-ol; hydrochloride CHEMBL1195937 (1R)-1alpha-(Aminomethyl)-3,4-dihydro-3alpha-phenyl-6-methoxy-1H-2-benzopyran-5-ol BDBM50008830
Inchi Key	CJSINCRQHDFMNW-HOTGVXAUSA-N
Inchi ID	InChI=1S/C17H19NO3/c1-20-14-8-7-12-13(17(14)19)9-15(21-16(12)10-18)11-5-3-2-4-6-11/h2-8,15-16,19H,9-10,18H2,1H3/t15-,16-/m0/s1
PubChem CID	15711860
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50008830
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	247.0 nM	PMID1833546	BindingDB

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