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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Lysophosphatidic acid receptor 1
Species	Mus musculus (Mouse)
Gene	Lpar1
Synonym	VZG-1 {ECO:0000303\|PubMed:8922387, ECO:0000303\|PubMed:9600933} Rec1.3 {ECO:0000303\|PubMed:9013780} Lysophosphatidic acid receptor Edg-2 {ECO:0000303\|PubMed:9600933} lysophosphatidic acid receptor Edg-2 Lpar1 LPA1 receptor LPA-1 {ECO:0000303\|PubMed:9600933, ECO:0000303\|PubMed:9721207} LPA receptor 1 {ECO:0000305} LPA receptor 1 GPR26 endothelial differentiation gene 2, lysophosphatidic acid G-protein-coupled receptor, 2 EDG2 VZG1 [ Show all ]
Disease	N/A for non-human GPCRs
Length	364
Amino acid sequence	MAAASTSSPVISQPQFTAMNEQQCFYNESIAFFYNRSGKYLATEWNTVSKLVMGLGITVCVFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGAIPSVGWNCICDIDHCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMSRHSSGPRRNRDTMMSLLKTVVIVLGAFIVCWTPGLVLLLLDVCCPQCDVLAYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQILCCQRNENPNGPTEGSDRSASSLNHTILAGVHSNDHSVV
UniProt	P61793
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3621025
IUPHAR	272
DrugBank	N/A

Ligand

Name	oleoyl-thiophosphate
Molecular formula	C54H99O6PS
IUPAC name	[[(Z)-octadec-9-enoyl]oxy-[(Z)-octadec-9-enoyl]sulfanylphosphoryl] (Z)-octadec-9-enoate
Molecular weight	907.414
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	22.2
Synonyms	SCHEMBL1691879 GTPL6983 [[(Z)-octadec-9-enoyl]oxy-[(Z)-octadec-9-enoyl]sulfanylphosphoryl] (Z)-octadec-9-enoate D0K3GQ
Inchi Key	VZTWVTAPKVGVJL-IUPFWZBJSA-N
Inchi ID	InChI=1S/C54H99O6PS/c1-4-7-10-13-16-19-22-25-28-31-34-37-40-43-46-49-52(55)59-61(58,60-53(56)50-47-44-41-38-35-32-29-26-23-20-17-14-11-8-5-2)62-54(57)51-48-45-42-39-36-33-30-27-24-21-18-15-12-9-6-3/h25-30H,4-24,31-51H2,1-3H3/b28-25-,29-26-,30-27-
PubChem CID	73755251
ChEMBL	N/A
IUPHAR	6983
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
EC50	193.0 nM	PMID20729877	IUPHAR

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