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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Succinate receptor 1
Species	Homo sapiens (Human)
Gene	SUCNR1
Synonym	succinate receptor 1 succinate receptor P2Y purinoceptor 1-like P2Y purinoceptor 1 GPR91 G-protein coupled receptor 91 G protein-coupled receptor 91 SUCNR1 [ Show all ]
Disease	N/A
Length	334
Amino acid sequence	MLGIMAWNATCKNWLAAEAALEKYYLSIFYGIEFVVGVLGNTIVVYGYIFSLKNWNSSNIYLFNLSVSDLAFLCTLPMLIRSYANGNWIYGDVLCISNRYVLHANLYTSILFLTFISIDRYLIIKYPFREHLLQKKEFAILISLAIWVLVTLELLPILPLINPVITDNGTTCNDFASSGDPNYNLIYSMCLTLLGFLIPLFVMCFFYYKIALFLKQRNRQVATALPLEKPLNLVIMAVVIFSVLFTPYHVMRNVRIASRLGSWKQYQCTQVVINSFYIVTRPLAFLNSVINPVFYFLLGDHFRDMLMNQLRHNFKSLTSFSRWAHELLLSFREK
UniProt	Q9BXA5
Protein Data Bank	N/A
GPCR-HGmod model	Q9BXA5
3D structure model	This predicted structure model is from GPCR-EXP Q9BXA5.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2150838
IUPHAR	166
DrugBank	BE0002258

Ligand

Name	(S)-2-chlorosuccinic acid
Molecular formula	C4H5ClO4
IUPAC name	(2S)-2-chlorobutanedioic acid
Molecular weight	152.53
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	-0.1
Synonyms	EINECS 224-092-9 SCHEMBL2782669 C-03116 GTPL9634 VC30308 (2S)-2-chlorobutanedioic acid D23232NSUY L-Chlorosuccinic acid 198C338 ACM4198338 FCH838986 UNII-D23232NSUY CC-01350 I04-0901 ZINC2018557 DB-050829 PubChem6255 4198-33-8 AKOS017344893 FT-0605208 UNII-E7056CM1PK component QEGKXSHUKXMDRW-REOHCLBHSA-N Chlorosuccinic acid, (S)- KB-04969 (S)-Chlorosuccinic acid [ Show all ]
Inchi Key	QEGKXSHUKXMDRW-REOHCLBHSA-N
Inchi ID	InChI=1S/C4H5ClO4/c5-2(4(8)9)1-3(6)7/h2H,1H2,(H,6,7)(H,8,9)/t2-/m0/s1
PubChem CID	9793861
ChEMBL	N/A
IUPHAR	9634
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
EC50	72000.0 nM	PMID28160606	IUPHAR

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