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Name | Lysophosphatidic acid receptor 3 |
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Species | Mus musculus (Mouse) |
Gene | Lpar3 |
Synonym | Edg7 endothelial differentiation gene 7, lysophosphatidic acid G-protein-coupled receptor 7 LPA receptor 3 LPA-3 LPA3 receptor [ Show all ] |
Disease | N/A for non-human GPCRs |
Length | 354 |
Amino acid sequence | MNECHYDKRMDFFYNRSNTDTADEWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVITNRKFHFPFYYLLANLAAADFFAGIAYVFLMFNTGPVSKTLTVNRWFLRQGLLDTSLTASLANLLVIAVERHMSIMRMRVHSNLTKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLIFWTVSNLLAFFIMVAVYVRIYMYVKRKTNVLSPHTSGSISRRRAPMKLMKTVMTVLGAFVVCWTPGLVVLLLDGLNCKQCNVQHVKRWFLLLALLNSVMNPIIYSYKDEDMYNTMRKMICCALQDSNTERRPSRNPSTIHSRSETGSQYLEDSISQGPVCNKNGS |
UniProt | Q9EQ31 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | N/A |
IUPHAR | 274 |
DrugBank | N/A |
Name | dodecyl-thiophosphate |
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Molecular formula | C12H27O3PS |
IUPAC name | dodecoxy-dihydroxy-sulfanylidene-lambda5-phosphane |
Molecular weight | 282.379 |
Hydrogen bond acceptor | 4 |
Hydrogen bond donor | 2 |
XlogP | 5.8 |
Synonyms | SCHEMBL40052 D04KQT GTPL6990 CHEMBL191365 Thiophosphoric acid dodecyl ester [ Show all ] |
Inchi Key | ISWBBUXCFWZBKC-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C12H27O3PS/c1-2-3-4-5-6-7-8-9-10-11-12-15-16(13,14)17/h2-12H2,1H3,(H2,13,14,17) |
PubChem CID | 10468943 |
ChEMBL | CHEMBL191365 |
IUPHAR | 6990 |
BindingDB | 50170860 |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand has a partition coefficient log P greater than 5. |
Parameter | Value | Reference | Database source |
---|---|---|---|
Ki | 13.0 nM | PMID16033271 | IUPHAR |
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