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GPCR

NameLysophosphatidic acid receptor 3
SpeciesMus musculus (Mouse)
GeneLpar3
SynonymEdg7
endothelial differentiation gene 7, lysophosphatidic acid G-protein-coupled receptor 7
LPA receptor 3
LPA-3
LPA3 receptor
[ Show all ]
DiseaseN/A for non-human GPCRs
Length354
Amino acid sequenceMNECHYDKRMDFFYNRSNTDTADEWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVITNRKFHFPFYYLLANLAAADFFAGIAYVFLMFNTGPVSKTLTVNRWFLRQGLLDTSLTASLANLLVIAVERHMSIMRMRVHSNLTKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLIFWTVSNLLAFFIMVAVYVRIYMYVKRKTNVLSPHTSGSISRRRAPMKLMKTVMTVLGAFVVCWTPGLVVLLLDGLNCKQCNVQHVKRWFLLLALLNSVMNPIIYSYKDEDMYNTMRKMICCALQDSNTERRPSRNPSTIHSRSETGSQYLEDSISQGPVCNKNGS
UniProtQ9EQ31
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLN/A
IUPHAR274
DrugBankN/A

Ligand

Namedodecyl-thiophosphate
Molecular formulaC12H27O3PS
IUPAC namedodecoxy-dihydroxy-sulfanylidene-lambda5-phosphane
Molecular weight282.379
Hydrogen bond acceptor4
Hydrogen bond donor2
XlogP5.8
SynonymsSCHEMBL40052
D04KQT
GTPL6990
CHEMBL191365
Thiophosphoric acid dodecyl ester
[ Show all ]
Inchi KeyISWBBUXCFWZBKC-UHFFFAOYSA-N
Inchi IDInChI=1S/C12H27O3PS/c1-2-3-4-5-6-7-8-9-10-11-12-15-16(13,14)17/h2-12H2,1H3,(H2,13,14,17)
PubChem CID10468943
ChEMBLCHEMBL191365
IUPHAR6990
BindingDB50170860
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand has a partition coefficient log P greater than 5.

Experimental Data

ParameterValueReferenceDatabase source
Ki13.0 nMPMID16033271IUPHAR

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