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Name | Lysophosphatidic acid receptor 3 |
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Species | Mus musculus (Mouse) |
Gene | Lpar3 |
Synonym | Edg7 endothelial differentiation gene 7, lysophosphatidic acid G-protein-coupled receptor 7 LPA receptor 3 LPA-3 LPA3 receptor [ Show all ] |
Disease | N/A for non-human GPCRs |
Length | 354 |
Amino acid sequence | MNECHYDKRMDFFYNRSNTDTADEWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVITNRKFHFPFYYLLANLAAADFFAGIAYVFLMFNTGPVSKTLTVNRWFLRQGLLDTSLTASLANLLVIAVERHMSIMRMRVHSNLTKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLIFWTVSNLLAFFIMVAVYVRIYMYVKRKTNVLSPHTSGSISRRRAPMKLMKTVMTVLGAFVVCWTPGLVVLLLDGLNCKQCNVQHVKRWFLLLALLNSVMNPIIYSYKDEDMYNTMRKMICCALQDSNTERRPSRNPSTIHSRSETGSQYLEDSISQGPVCNKNGS |
UniProt | Q9EQ31 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | N/A |
IUPHAR | 274 |
DrugBank | N/A |
Name | D0Z6DG |
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Molecular formula | C23H42NaO6PS |
IUPAC name | sodium;[(3R,4S)-4-[hydroxy(oxido)phosphinothioyl]oxyoxan-3-yl] (Z)-octadec-9-enoate |
Molecular weight | 500.607 |
Hydrogen bond acceptor | 7 |
Hydrogen bond donor | 1 |
XlogP | None |
Synonyms | N/A |
Inchi Key | DFEVXZSENXLXQQ-LYOQJJATSA-M |
Inchi ID | InChI=1S/C23H43O6PS.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-23(24)28-22-20-27-19-18-21(22)29-30(25,26)31;/h9-10,21-22H,2-8,11-20H2,1H3,(H2,25,26,31);/q;+1/p-1/b10-9-;/t21-,22+;/m0./s1 |
PubChem CID | 23701997 |
ChEMBL | N/A |
IUPHAR | 6984 |
BindingDB | N/A |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand is heavier than 500 daltons. Partition coefficient log P of this ligand is not available. |
Parameter | Value | Reference | Database source |
---|---|---|---|
EC50 | 0.5 nM | PMID18781939 | IUPHAR |
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