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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Sphingosine 1-phosphate receptor 4
Species	Mus musculus (Mouse)
Gene	S1pr4
Synonym	S1P4 receptor S1P4 S1P receptor Edg-6 S1P receptor 4 Lysophospholipid receptor C1 endothelial differentiation, G protein-coupled receptor 6 Endothelial differentiation G-protein coupled receptor 6 edg6 Sphingosine 1-phosphate receptor Edg-6 [ Show all ]
Disease	N/A for non-human GPCRs
Length	386
Amino acid sequence	MNISTWSTLVTPESCHRLAASGHSLLIVLHYNHSGRLASRGGSEDGGGLGMLRGPSVAAGCLVVLENAMVLAAIAIYMRSRRWVYYCLLNITLSDLLTGLAYVVNVLLSGTRTFQLSPVHWFLREGLLFMALAASTFSLLFTAGERFATMVRVAESGATKTSRVYGCIGLCWLLAAILGLLPLLGWNCVCAFPRCSSLLPLYSKGYVLFCVVVFALILVAILSLYGAIFRVVRANGQKSPRPPARRKSRRLLNTVLMILVAFVVCWGPLFGLLLADIFGSNVWAQEYLRGMDWILALAVFNSAINPLIYSFRSREVQRAVLAFLCCGCLWLGLRGPGDCLTRITEAHSGASTTDSSLRPRDSFRTSRSLSFRMREPLSSISSVRST
UniProt	Q9Z0L1
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	N/A
IUPHAR	278
DrugBank	N/A

Ligand

Name	KRP 203-phosphate
Molecular formula	C23H25ClNO6PS
IUPAC name	[2-amino-4-[2-chloro-4-(3-phenoxyphenyl)sulfanylphenyl]-2-(hydroxymethyl)butyl] dihydrogen phosphate
Molecular weight	509.938
Hydrogen bond acceptor	8
Hydrogen bond donor	4
XlogP	1.0
Synonyms	GTPL2923 [2-amino-2-(2-{2-chloro-4-[(3-phenoxyphenyl)sulfanyl]phenyl}ethyl)-3-hydroxypropoxy]phosphonic acid D0U7YK SCHEMBL20478074
Inchi Key	BZVUYJGCYLMFGX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H25ClNO6PS/c24-22-14-21(10-9-17(22)11-12-23(25,15-26)16-30-32(27,28)29)33-20-8-4-7-19(13-20)31-18-5-2-1-3-6-18/h1-10,13-14,26H,11-12,15-16,25H2,(H2,27,28,29)
PubChem CID	56947075
ChEMBL	N/A
IUPHAR	2923
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
EC50	10.0 nM	PMID17898319	IUPHAR

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