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Name | Lysophosphatidic acid receptor 3 |
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Species | Mus musculus (Mouse) |
Gene | Lpar3 |
Synonym | Edg7 endothelial differentiation gene 7, lysophosphatidic acid G-protein-coupled receptor 7 LPA receptor 3 LPA-3 LPA3 receptor [ Show all ] |
Disease | N/A for non-human GPCRs |
Length | 354 |
Amino acid sequence | MNECHYDKRMDFFYNRSNTDTADEWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVITNRKFHFPFYYLLANLAAADFFAGIAYVFLMFNTGPVSKTLTVNRWFLRQGLLDTSLTASLANLLVIAVERHMSIMRMRVHSNLTKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLIFWTVSNLLAFFIMVAVYVRIYMYVKRKTNVLSPHTSGSISRRRAPMKLMKTVMTVLGAFVVCWTPGLVVLLLDGLNCKQCNVQHVKRWFLLLALLNSVMNPIIYSYKDEDMYNTMRKMICCALQDSNTERRPSRNPSTIHSRSETGSQYLEDSISQGPVCNKNGS |
UniProt | Q9EQ31 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | N/A |
IUPHAR | 274 |
DrugBank | N/A |
Name | NAEPA |
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Molecular formula | C20H40NO5P |
IUPAC name | 2-[[(E)-octadec-9-enoyl]amino]ethyl dihydrogen phosphate |
Molecular weight | 405.516 |
Hydrogen bond acceptor | 5 |
Hydrogen bond donor | 3 |
XlogP | 5.2 |
Synonyms | D0R8LB 2-{[(9E)-Octadec-9-enoyl]amino}ethyl dihydrogen phosphate N-acyl ethanolamide phosphate API0008297 NCGC00165839-01 [ Show all ] |
Inchi Key | BCSUWOZFWWBYSX-MDZDMXLPSA-N |
Inchi ID | InChI=1S/C20H40NO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(22)21-18-19-26-27(23,24)25/h9-10H,2-8,11-19H2,1H3,(H,21,22)(H2,23,24,25)/b10-9+ |
PubChem CID | 17757220 |
ChEMBL | N/A |
IUPHAR | 6982 |
BindingDB | N/A |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand has a partition coefficient log P greater than 5. |
Parameter | Value | Reference | Database source |
---|---|---|---|
EC50 | <5000.0 nM | PMID18781939 | IUPHAR |
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