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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Free fatty acid receptor 4
Species	Mus musculus (Mouse)
Gene	Ffar4
Synonym	Omega-3 fatty acid receptor 1 O3FAR1 GT01 GPR129 GPR120 G-protein-coupled receptor GT01 G-protein coupled receptor GT01 G-protein coupled receptor 120 G protein-coupled receptor 129 G protein-coupled receptor 120 FFA4 receptor PGR4 [ Show all ]
Disease	N/A for non-human GPCRs
Length	361
Amino acid sequence	MSPECAQTTGPGPSHTLDQVNRTHFPFFSDVKGDHRLVLSVVETTVLGLIFVVSLLGNVCALVLVARRRRRGATASLVLNLFCADLLFTSAIPLVLVVRWTEAWLLGPVVCHLLFYVMTMSGSVTILTLAAVSLERMVCIVRLRRGLSGPGRRTQAALLAFIWGYSALAALPLCILFRVVPQRLPGGDQEIPICTLDWPNRIGEISWDVFFVTLNFLVPGLVIVISYSKILQITKASRKRLTLSLAYSESHQIRVSQQDYRLFRTLFLLMVSFFIMWSPIIITILLILIQNFRQDLVIWPSLFFWVVAFTFANSALNPILYNMSLFRNEWRKIFCCFFFPEKGAIFTDTSVRRNDLSVISS
UniProt	Q7TMA4
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2052036
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL3968537
Molecular formula	C21H20O4
IUPAC name	3-[5-(3-cyclobutyloxyphenyl)-1-benzofuran-2-yl]propanoic acid
Molecular weight	336.387
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	4.6
Synonyms	BDBM50203659
Inchi Key	AIGFQVBWSVEVLF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H20O4/c22-21(23)10-8-19-13-16-11-15(7-9-20(16)25-19)14-3-1-6-18(12-14)24-17-4-2-5-17/h1,3,6-7,9,11-13,17H,2,4-5,8,10H2,(H,22,23)
PubChem CID	134151115
ChEMBL	CHEMBL3968537
IUPHAR	N/A
BindingDB	50203659
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Activity	66.0 %	PMID27815121	ChEMBL
EC50	35.0 nM	PMID27815121	BindingDB,ChEMBL

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