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Name | Melatonin receptor type 1C |
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Species | Gallus gallus (Chicken) |
Gene | |
Synonym | CKB Mel-1C-R Mel1c receptor |
Disease | N/A for non-human GPCRs |
Length | 346 |
Amino acid sequence | MERPGSNGSCSGCRLEGGPAARAASGLAAVLIVTIVVDVLGNALVILSVLRNKKLRNAGNIFVVSLSVADLVVAVYPYPLILSAIFHNGWTMGNIHCQISGFLMGLSVIGSIFNITAIAINRYCYICHSLRYDKLFNLKNTCCYICLTWTLTVVAIVPNFFVGSLQYDPRIYSCTFAQTVSTSYTITVVVVHFIVPLSIVTFCYLRIWILVIQVKHRVRQDCKQKIRAADIRNFLTMFVVFVLFAVCWGPLNFIGLAVSINPSKVQPHIPEWLFVLSYFMAYFNSCLNAVIYGLLNQNFRKEYKRILLMLRTPRLLFIDVSKGGTEGLKSKPSPAVTNNNQAEIHL |
UniProt | P49288 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL3196 |
IUPHAR | N/A |
DrugBank | N/A |
Name | 5-hydroxyethoxy-N-acetyltryptamine |
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Molecular formula | C14H18N2O3 |
IUPAC name | N-[2-[5-(2-hydroxyethoxy)-1H-indol-3-yl]ethyl]acetamide |
Molecular weight | 262.309 |
Hydrogen bond acceptor | 3 |
Hydrogen bond donor | 3 |
XlogP | 0.1 |
Synonyms | D08SGV N-[2-[5-(2-hydroxyethoxy)-1H-indol-3-yl]ethyl]acetamide CHEMBL126809 214416-49-6 DTXSID40445810 [ Show all ] |
Inchi Key | CZPLTTWZQPLXMQ-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C14H18N2O3/c1-10(18)15-5-4-11-9-16-14-3-2-12(8-13(11)14)19-7-6-17/h2-3,8-9,16-17H,4-7H2,1H3,(H,15,18) |
PubChem CID | 10849065 |
ChEMBL | CHEMBL126809 |
IUPHAR | 1345 |
BindingDB | N/A |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand satisfies Lipinski's rule of five. |
Parameter | Value | Reference | Database source |
---|---|---|---|
Relative affinity | 492.0 - | PMID9748358 | ChEMBL |
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