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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	D(4) dopamine receptor
Species	Mus musculus (Mouse)
Gene	Drd4
Synonym	d(2C) dopamine receptor D4 receptor D4R Dopamine D4 receptor dopamine receptor 4
Disease	N/A for non-human GPCRs
Length	387
Amino acid sequence	MGNSSATEDGGLLAGRGPESLGTGAGLGGAGAAALVGGVLLIGLVLAGNSLVCVSVASERTLQTPTNYFIVSLAAADLLLAVLVLPLFVYSEVQGGVWLLSPRLCDTLMAMDVMLCTASIFNLCAISVDRFVAVTVPLRYNQQGQCQLLLIAATWLLSAAVASPVVCGLNDVPGRDPAVCCLENRDYVVYSSVCSFFLPCPLMLLLYWATFRGLRRWEAARHTKLHSRAPRRPSGPGPPVSDPTQGPFFPDCPPPLPSLRTSPSDSSRPESELSQRPCSPGCLLADAALPQPPEPSSRRRRGAKITGRERKAMRVLPVVVGAFLVCWTPFFVVHITRALCPACFVSPRLVSAVTWLGYVNSALNPIIYTIFNAEFRSVFRKTLRLRC
UniProt	P51436
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2574
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL3900699
Molecular formula	C22H26N2O4
IUPAC name	1-(2,3-dihydroindol-1-yl)-2-[(2S)-2-[(3-methoxyphenoxy)methyl]morpholin-4-yl]ethanone
Molecular weight	382.46
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	2.7
Synonyms	US9079895, 24s BDBM186936 KJWABLDVLWKPKR-FQEVSTJZSA-N (S)-1-(Indolin-1-yl)-2-(2-((3-methoxyphenoxy)methyl)morpholino)ethanone SCHEMBL14061835
Inchi Key	KJWABLDVLWKPKR-FQEVSTJZSA-N
Inchi ID	InChI=1S/C22H26N2O4/c1-26-18-6-4-7-19(13-18)28-16-20-14-23(11-12-27-20)15-22(25)24-10-9-17-5-2-3-8-21(17)24/h2-8,13,20H,9-12,14-16H2,1H3/t20-/m0/s1
PubChem CID	71062768
ChEMBL	CHEMBL3900699
IUPHAR	N/A
BindingDB	186936
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	2486.0 nM	None	ChEMBL

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