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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Cysteinyl leukotriene receptor 1
Species	Mus musculus (Mouse)
Gene	Cysltr1
Synonym	CYSLT1R CysLTR1 Cysteinyl leukotriene D4 receptor CysLT1 receptor HG55 leukotriene D4 receptor LTD4 LTD4 receptor [ Show all ]
Disease	N/A for non-human GPCRs
Length	352
Amino acid sequence	MYLQGTKQTFLENMNGTENLTTSLINNTCHDTIDEFRNQVYSTMYSVISVVGFFGNSFVLYVLIKTYHEKSAFQVYMINLAIADLLCVCTLPLRVVYYVHKGKWLFGDFLCRLTTYALYVNLYCSIFFMTAMSFFRCVAIVFPVQNINLVTQKKARFVCIGIWIFVILTSSPFLMYKSYQDEKNNTKCFEPPQNNQAKKYVLILHYVSLFFGFIIPFVTIIVCYTMIILTLLKNTMKKNMPSRRKAIGMIIVVTAAFLVSFMPYHIQRTIHLHLLHSETRPCDSVLRMQKSVVITLSLAASNCCFDPLLYFFSGGNFRRRLSTFRKHSLSSMTYVPKKKASLPEKGEEICNE
UniProt	Q99JA4
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3808269
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL3809189
Molecular formula	C29H19ClFN3O3
IUPAC name	3-[(E)-3-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]anilino]-3-oxoprop-1-enyl]-5-fluoro-1H-indole-2-carboxylic acid
Molecular weight	511.937
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	6.5
Synonyms	BDBM50172339
Inchi Key	SKYIYJVEAPMJBU-VFBBEJETSA-N
Inchi ID	InChI=1S/C29H19ClFN3O3/c30-19-7-5-18-6-10-21(32-26(18)15-19)9-4-17-2-1-3-22(14-17)33-27(35)13-11-23-24-16-20(31)8-12-25(24)34-28(23)29(36)37/h1-16,34H,(H,33,35)(H,36,37)/b9-4+,13-11+
PubChem CID	127043244
ChEMBL	CHEMBL3809189
IUPHAR	N/A
BindingDB	50172339
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Inhibition	50.0 %	PMID26985325	ChEMBL

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