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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Olfactory receptor 5K1
Species	Homo sapiens (Human)
Gene	OR5K1
Synonym	HTPCRX10 Olfactory receptor OR3-8
Disease	N/A
Length	308
Amino acid sequence	MAEENHTMKNEFILTGFTDHPELKTLLFVVFFAIYLITVVGNISLVALIFTHRRLHTPMYIFLGNLALVDSCCACAITPKMLENFFSENKRISLYECAVQFYFLCTVETADCFLLAAMAYDRYVAICNPLQYHIMMSKKLCIQMTTGAFIAGNLHSMIHVGLVFRLVFCGSNHINHFYCDILPLYRLSCVDPYINELVLFIFSGSVQVFTIGSVLISYLYILLTIFKMKSKEGRAKAFSTCASHFLSVSLFYGSLFFMYVRPNLLEEGDKDIPAAILFTIVVPLLNPFIYSLRNREVISVLRKILMKK
UniProt	Q8NHB7
Protein Data Bank	N/A
GPCR-HGmod model	Q8NHB7
3D structure model	This predicted structure model is from GPCR-EXP Q8NHB7.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3721312
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	Ambrettolid
Molecular formula	C16H28O2
IUPAC name	(8Z)-1-oxacycloheptadec-8-en-2-one
Molecular weight	252.398
Hydrogen bond acceptor	2
Hydrogen bond donor	0
XlogP	5.5
Synonyms	AI3-30957 FEMA 2758 NCGC00178599-01 SCHEMBL1539181 095I377U8F 16-Hydroxy-7-hexadecenoic acid lactone, cis- Ambrettolide LS-98808 Oxacycloheptadec-8-en-2-one (8Z)-1-oxacycloheptadec-8-en-2-one 8Z-oxacycloheptadec-8-en-2-one CHEMBL3727440 Musk natural OXACYCLOHEPTADEC-8-EN-2-ONE, (Z)- (Z)-7-Hexadecen-16-olide 123-69-3 AKOS015914244 Hexadec-7-en-16-olide NVIPUOMWGQAOIT-RQOWECAXSA-N UNII-095I377U8F 17598-28-6 AN-43492 Musk ambrette (natural) Oxacycloheptadec-8-en-2-one 100 microg/mL in Cyclohexane (8Z)-Oxacycloheptadec-8-en-2-one AC1NSM2Y EINECS 204-644-5 Natural musk ambrette S845 (Z)-Oxacycloheptadec-8-en-2-one 16-Hydroxy-7-hexadecenoic acid lactone I14-43954 omega-6-Hexadecenlactone ZINC31771385 7-Hexadecen-16-olid Musk ambrette, natural Oxacycloheptadec-8-en-2-one, (8Z)- (Z)-7-Hexadecen-1,16-olide [ Show all ]
Inchi Key	NVIPUOMWGQAOIT-RQOWECAXSA-N
Inchi ID	InChI=1S/C16H28O2/c17-16-14-12-10-8-6-4-2-1-3-5-7-9-11-13-15-18-16/h2,4H,1,3,5-15H2/b4-2-
PubChem CID	5365703
ChEMBL	CHEMBL3727440
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Inhibition	50.0 %	None	ChEMBL

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