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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Putative P2Y purinoceptor 10
Species	Mus musculus (Mouse)
Gene	P2ry10
Synonym	P2RY10 P2Y10 purinergic receptor P2Y purinergic receptor P2Y, G-protein coupled 10 purinergic receptor P2Y10
Disease	N/A for non-human GPCRs
Length	328
Amino acid sequence	MGSNSTSSAESNCNATYLPFQYSLYATTYIFIFIPGLLANSAALWVLCRFISKKNKAIIFMINLSVADLAHILSLPLRIYYYINRHWPFQRALCLLCFYLKYLNMYASIFFLTCISLQRCLFLLKPFRARNWKRRYDVGISAVIWIVVGTACLPFPILRNAGLANSTDSCFADLGYKQMDAVVLVTMVVIAELAGFVIPVITIACCTWKTTVSLKHPPIAFQGISERKKALRMVFMCAAVFVICFTPYHINFIFYTMVKESIITSCPTVKSTLYFHPFSLCLASLCCLLDPILYYFMASEFRDQLSRHGSSVTRSRLMSRESGSSMVN
UniProt	Q8BFU7
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3562168
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEBI:52649
Molecular formula	C24H46NO9P
IUPAC name	(2S)-2-amino-3-[hydroxy-[(2R)-2-hydroxy-3-[(Z)-octadec-9-enoyl]oxypropoxy]phosphoryl]oxypropanoic acid
Molecular weight	523.604
Hydrogen bond acceptor	10
Hydrogen bond donor	4
XlogP	2.1
Synonyms	PS(18:1/0:0) CHEMBL1742484 1-oleoyl-sn-glycero-3-phospho-l-serine LMGP03050001 O-[hydroxy({(2R)-2-hydroxy-3-[(9Z)-octadec-9-enoyloxy]propyl}oxy)phosphoryl]-L-serine SCHEMBL15928095 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoserine JZWNYZVVZXZRRH-YFKVPUFHSA-N 1-oleoyl-sn-glycero-3-phosphoserine LPS(18:1) PS(18:1(9Z)/0:0) 1-O-oleoyl-sn-glycero-3-phosphoserine L-Serine, 2-hydroxy-3-[(1-oxo-9-octadecenyl)oxy]propyl hydrogen phosphate (ester), [R-(Z)]- BDBM50096349 O-(1-O-Oleoyl-L-glycero-3-phospho)-L-serine [ Show all ]
Inchi Key	JZWNYZVVZXZRRH-YFKVPUFHSA-N
Inchi ID	InChI=1S/C24H46NO9P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-23(27)32-18-21(26)19-33-35(30,31)34-20-22(25)24(28)29/h9-10,21-22,26H,2-8,11-20,25H2,1H3,(H,28,29)(H,30,31)/b10-9-/t21-,22+/m1/s1
PubChem CID	9547099
ChEMBL	CHEMBL1742484
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
EC50	24.55 nM	PMID27077565	ChEMBL
EC50	25.0 nM	PMID27077565	ChEMBL
Emax	12.5 %	PMID27077565	ChEMBL
Intrinsic activity	0.073 -	PMID27077565	ChEMBL

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