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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Probable G-protein coupled receptor 34
Species	Mus musculus (Mouse)
Gene	Gpr34
Synonym	GPR34
Disease	N/A for non-human GPCRs
Length	375
Amino acid sequence	MTTTSVDSWLCSSHGMHFITNYSDQASQNFSGVPNVTSCPMDEKLLSTVLTTFYSVIFLVGLVGNIIALYVFLGIHRKRNSIQIYLLNVAVADLLLIFCLPFRIMYHINQNKWTLGVILCKVVGTLFYMNMYISIILLGFISLDRYIKINRSIQQRRAITTKQSIYVCCIVWTVALAGFLTMIILTLKKGGHNSTMCFHYRDRHNAKGEAIFNFVLVVMFWLIFLLIILSYIKIGKNLLRISKRRSKFPNSGKYATTARNSFIVLIIFTICFVPYHAFRFIYISSQLNVSSCYWKEIIHKTNEIMLVFSSFNSCLDPVMYFLMSSNIRKIMCQLLFRRFQSEASRSESTSEFKPGHSLHDLSVTVKMPQYSTKGN
UniProt	Q9R1K6
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL1075291
IUPHAR	101
DrugBank	N/A

Ligand

Name	CHEBI:52649
Molecular formula	C24H46NO9P
IUPAC name	(2S)-2-amino-3-[hydroxy-[(2R)-2-hydroxy-3-[(Z)-octadec-9-enoyl]oxypropoxy]phosphoryl]oxypropanoic acid
Molecular weight	523.604
Hydrogen bond acceptor	10
Hydrogen bond donor	4
XlogP	2.1
Synonyms	PS(18:1/0:0) CHEMBL1742484 1-oleoyl-sn-glycero-3-phospho-l-serine LMGP03050001 O-[hydroxy({(2R)-2-hydroxy-3-[(9Z)-octadec-9-enoyloxy]propyl}oxy)phosphoryl]-L-serine SCHEMBL15928095 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoserine JZWNYZVVZXZRRH-YFKVPUFHSA-N 1-oleoyl-sn-glycero-3-phosphoserine LPS(18:1) PS(18:1(9Z)/0:0) 1-O-oleoyl-sn-glycero-3-phosphoserine L-Serine, 2-hydroxy-3-[(1-oxo-9-octadecenyl)oxy]propyl hydrogen phosphate (ester), [R-(Z)]- BDBM50096349 O-(1-O-Oleoyl-L-glycero-3-phospho)-L-serine [ Show all ]
Inchi Key	JZWNYZVVZXZRRH-YFKVPUFHSA-N
Inchi ID	InChI=1S/C24H46NO9P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-23(27)32-18-21(26)19-33-35(30,31)34-20-22(25)24(28)29/h9-10,21-22,26H,2-8,11-20,25H2,1H3,(H,28,29)(H,30,31)/b10-9-/t21-,22+/m1/s1
PubChem CID	9547099
ChEMBL	CHEMBL1742484
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
EC50	239.88 nM	PMID27077565	ChEMBL
EC50	240.0 nM	PMID27077565	ChEMBL
Emax	9.5 %	PMID27077565	ChEMBL
Intrinsic activity	0.33 -	PMID27077565	ChEMBL

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