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Name | Putative P2Y purinoceptor 10 |
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Species | Homo sapiens (Human) |
Gene | P2RY10 |
Synonym | P2Y-like receptor P2RY10 purinergic receptor P2Y purinergic receptor P2Y, G-protein coupled 10 purinergic receptor P2Y10 [ Show all ] |
Disease | N/A |
Length | 339 |
Amino acid sequence | MANLDKYTETFKMGSNSTSTAEIYCNVTNVKFQYSLYATTYILIFIPGLLANSAALWVLCRFISKKNKAIIFMINLSVADLAHVLSLPLRIYYYISHHWPFQRALCLLCFYLKYLNMYASICFLTCISLQRCFFLLKPFRARDWKRRYDVGISAAIWIVVGTACLPFPILRSTDLNNNKSCFADLGYKQMNAVALVGMITVAELAGFVIPVIIIAWCTWKTTISLRQPPMAFQGISERQKALRMVFMCAAVFFICFTPYHINFIFYTMVKETIISSCPVVRIALYFHPFCLCLASLCCLLDPILYYFMASEFRDQLSRHGSSVTRSRLMSKESGSSMIG |
UniProt | O00398 |
Protein Data Bank | N/A |
GPCR-HGmod model | O00398 |
3D structure model | This predicted structure model is from GPCR-EXP O00398. |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL3562166 |
IUPHAR | 165 |
DrugBank | N/A |
Name | CHEMBL3577181 |
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Molecular formula | C26H44NO9P |
IUPAC name | (2S)-2-amino-3-[hydroxy-[3-[3-(4-undecoxyphenyl)propanoyloxy]propoxy]phosphoryl]oxypropanoic acid |
Molecular weight | 545.61 |
Hydrogen bond acceptor | 10 |
Hydrogen bond donor | 3 |
XlogP | 2.5 |
Synonyms | BDBM50096502 |
Inchi Key | LSCJPEVNUYGUBE-DEOSSOPVSA-N |
Inchi ID | InChI=1S/C26H44NO9P/c1-2-3-4-5-6-7-8-9-10-18-33-23-15-12-22(13-16-23)14-17-25(28)34-19-11-20-35-37(31,32)36-21-24(27)26(29)30/h12-13,15-16,24H,2-11,14,17-21,27H2,1H3,(H,29,30)(H,31,32)/t24-/m0/s1 |
PubChem CID | 122177527 |
ChEMBL | CHEMBL3577181 |
IUPHAR | N/A |
BindingDB | 50096502 |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand is heavier than 500 daltons. |
Parameter | Value | Reference | Database source |
---|---|---|---|
EC50 | 54.95 nM | PMID25970039 | ChEMBL |
EC50 | 55.0 nM | PMID25970039 | BindingDB |
EC50 | 56.0 nM | PMID25970039 | BindingDB,ChEMBL |
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