You can:
Name | Probable G-protein coupled receptor 34 |
---|---|
Species | Homo sapiens (Human) |
Gene | GPR34 |
Synonym | GPR34 |
Disease | N/A |
Length | 381 |
Amino acid sequence | MRSHTITMTTTSVSSWPYSSHRMRFITNHSDQPPQNFSATPNVTTCPMDEKLLSTVLTTSYSVIFIVGLVGNIIALYVFLGIHRKRNSIQIYLLNVAIADLLLIFCLPFRIMYHINQNKWTLGVILCKVVGTLFYMNMYISIILLGFISLDRYIKINRSIQQRKAITTKQSIYVCCIVWMLALGGFLTMIILTLKKGGHNSTMCFHYRDKHNAKGEAIFNFILVVMFWLIFLLIILSYIKIGKNLLRISKRRSKFPNSGKYATTARNSFIVLIIFTICFVPYHAFRFIYISSQLNVSSCYWKEIVHKTNEIMLVLSSFNSCLDPVMYFLMSSNIRKIMCQLLFRRFQGEPSRSESTSEFKPGYSLHDTSVAVKIQSSSKST |
UniProt | Q9UPC5 |
Protein Data Bank | N/A |
GPCR-HGmod model | Q9UPC5 |
3D structure model | This predicted structure model is from GPCR-EXP Q9UPC5. |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL3562165 |
IUPHAR | 101 |
DrugBank | N/A |
Name | CHEBI:52649 |
---|---|
Molecular formula | C24H46NO9P |
IUPAC name | (2S)-2-amino-3-[hydroxy-[(2R)-2-hydroxy-3-[(Z)-octadec-9-enoyl]oxypropoxy]phosphoryl]oxypropanoic acid |
Molecular weight | 523.604 |
Hydrogen bond acceptor | 10 |
Hydrogen bond donor | 4 |
XlogP | 2.1 |
Synonyms | PS(18:1(9Z)/0:0) 1-O-oleoyl-sn-glycero-3-phosphoserine L-Serine, 2-hydroxy-3-[(1-oxo-9-octadecenyl)oxy]propyl hydrogen phosphate (ester), [R-(Z)]- BDBM50096349 O-(1-O-Oleoyl-L-glycero-3-phospho)-L-serine [ Show all ] |
Inchi Key | JZWNYZVVZXZRRH-YFKVPUFHSA-N |
Inchi ID | InChI=1S/C24H46NO9P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-23(27)32-18-21(26)19-33-35(30,31)34-20-22(25)24(28)29/h9-10,21-22,26H,2-8,11-20,25H2,1H3,(H,28,29)(H,30,31)/b10-9-/t21-,22+/m1/s1 |
PubChem CID | 9547099 |
ChEMBL | CHEMBL1742484 |
IUPHAR | N/A |
BindingDB | N/A |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand is heavier than 500 daltons. |
Parameter | Value | Reference | Database source |
---|---|---|---|
EC50 | 549.54 nM | PMID25970039 | ChEMBL |
EC50 | 550.0 nM | PMID25970039 | ChEMBL |
zhanglabzhanggroup.org | +65-6601-1241 | Computing 1, 13 Computing Drive, Singapore 117417