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Name | Putative P2Y purinoceptor 10 |
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Species | Homo sapiens (Human) |
Gene | P2RY10 |
Synonym | P2Y-like receptor P2RY10 purinergic receptor P2Y purinergic receptor P2Y, G-protein coupled 10 purinergic receptor P2Y10 [ Show all ] |
Disease | N/A |
Length | 339 |
Amino acid sequence | MANLDKYTETFKMGSNSTSTAEIYCNVTNVKFQYSLYATTYILIFIPGLLANSAALWVLCRFISKKNKAIIFMINLSVADLAHVLSLPLRIYYYISHHWPFQRALCLLCFYLKYLNMYASICFLTCISLQRCFFLLKPFRARDWKRRYDVGISAAIWIVVGTACLPFPILRSTDLNNNKSCFADLGYKQMNAVALVGMITVAELAGFVIPVIIIAWCTWKTTISLRQPPMAFQGISERQKALRMVFMCAAVFFICFTPYHINFIFYTMVKETIISSCPVVRIALYFHPFCLCLASLCCLLDPILYYFMASEFRDQLSRHGSSVTRSRLMSKESGSSMIG |
UniProt | O00398 |
Protein Data Bank | N/A |
GPCR-HGmod model | O00398 |
3D structure model | This predicted structure model is from GPCR-EXP O00398. |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL3562166 |
IUPHAR | 165 |
DrugBank | N/A |
Name | CHEMBL3577160 |
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Molecular formula | C24H46NO9P |
IUPAC name | (2R)-2-amino-3-[hydroxy-[(2R)-2-hydroxy-3-[(Z)-octadec-9-enoyl]oxypropoxy]phosphoryl]oxypropanoic acid |
Molecular weight | 523.604 |
Hydrogen bond acceptor | 10 |
Hydrogen bond donor | 4 |
XlogP | 2.1 |
Synonyms | BDBM50096599 |
Inchi Key | JZWNYZVVZXZRRH-LUCICDSHSA-N |
Inchi ID | InChI=1S/C24H46NO9P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-23(27)32-18-21(26)19-33-35(30,31)34-20-22(25)24(28)29/h9-10,21-22,26H,2-8,11-20,25H2,1H3,(H,28,29)(H,30,31)/b10-9-/t21-,22-/m1/s1 |
PubChem CID | 122177508 |
ChEMBL | CHEMBL3577160 |
IUPHAR | N/A |
BindingDB | 50096599 |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand is heavier than 500 daltons. |
Parameter | Value | Reference | Database source |
---|---|---|---|
EC50 | <1000.0 nM | PMID25970039 | BindingDB,ChEMBL |
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