You can:
Name | Probable G-protein coupled receptor 174 |
---|---|
Species | Homo sapiens (Human) |
Gene | GPR174 |
Synonym | FKSG79 GPR174 |
Disease | N/A |
Length | 333 |
Amino acid sequence | MPANYTCTRPDGDNTDFRYFIYAVTYTVILVPGLIGNILALWVFYGYMKETKRAVIFMINLAIADLLQVLSLPLRIFYYLNHDWPFGPGLCMFCFYLKYVNMYASIYFLVCISVRRFWFLMYPFRFHDCKQKYDLYISIAGWLIICLACVLFPLLRTSDDTSGNRTKCFVDLPTRNVNLAQSVVMMTIGELIGFVTPLLIVLYCTWKTVLSLQDKYPMAQDLGEKQKALKMILTCAGVFLICFAPYHFSFPLDFLVKSNEIKSCLARRVILIFHSVALCLASLNSCLDPVIYYFSTNEFRRRLSRQDLHDSIQLHAKSFVSNHTASTMTPELC |
UniProt | Q9BXC1 |
Protein Data Bank | N/A |
GPCR-HGmod model | Q9BXC1 |
3D structure model | This predicted structure model is from GPCR-EXP Q9BXC1. |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL3562167 |
IUPHAR | 145 |
DrugBank | N/A |
Name | CHEMBL3577263 |
---|---|
Molecular formula | C27H46NO10P |
IUPAC name | (2S,3S)-2-amino-3-[hydroxy-[(2R)-2-hydroxy-3-[3-(3-undecoxyphenyl)propanoyloxy]propoxy]phosphoryl]oxybutanoic acid |
Molecular weight | 575.636 |
Hydrogen bond acceptor | 11 |
Hydrogen bond donor | 4 |
XlogP | 2.0 |
Synonyms | BDBM50096583 |
Inchi Key | GEYPUJKTNAJBTR-SYVJQLTCSA-N |
Inchi ID | InChI=1S/C27H46NO10P/c1-3-4-5-6-7-8-9-10-11-17-35-24-14-12-13-22(18-24)15-16-25(30)36-19-23(29)20-37-39(33,34)38-21(2)26(28)27(31)32/h12-14,18,21,23,26,29H,3-11,15-17,19-20,28H2,1-2H3,(H,31,32)(H,33,34)/t21-,23+,26-/m0/s1 |
PubChem CID | 122177590 |
ChEMBL | CHEMBL3577263 |
IUPHAR | N/A |
BindingDB | 50096583 |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons. |
Parameter | Value | Reference | Database source |
---|---|---|---|
EC50 | 39.81 nM | PMID25970039 | ChEMBL |
EC50 | 40.0 nM | PMID25970039 | BindingDB,ChEMBL |
zhanglabzhanggroup.org | +65-6601-1241 | Computing 1, 13 Computing Drive, Singapore 117417