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Name | N-formyl peptide receptor 3 |
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Species | Homo sapiens (Human) |
Gene | FPR3 |
Synonym | FMLP-related receptor II Lxa4r LXA4-R FPRL2 Fprl1 [ Show all ] |
Disease | N/A |
Length | 353 |
Amino acid sequence | METNFSIPLNETEEVLPEPAGHTVLWIFSLLVHGVTFVFGVLGNGLVIWVAGFRMTRTVNTICYLNLALADFSFSAILPFRMVSVAMREKWPFGSFLCKLVHVMIDINLFVSVYLITIIALDRCICVLHPAWAQNHRTMSLAKRVMTGLWIFTIVLTLPNFIFWTTISTTNGDTYCIFNFAFWGDTAVERLNVFITMAKVFLILHFIIGFSVPMSIITVCYGIIAAKIHRNHMIKSSRPLRVFAAVVASFFICWFPYELIGILMAVWLKEMLLNGKYKIILVLINPTSSLAFFNSCLNPILYVFMGRNFQERLIRSLPTSLERALTEVPDSAQTSNTDTTSASPPEETELQAM |
UniProt | P25089 |
Protein Data Bank | N/A |
GPCR-HGmod model | P25089 |
3D structure model | This predicted structure model is from GPCR-EXP P25089. |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | N/A |
IUPHAR | 224 |
DrugBank | N/A |
Name | CHEMBL2391442 |
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Molecular formula | C22H22IN3O4 |
IUPAC name | 2-[5-[(3,5-dimethoxyphenyl)methyl]-3-methyl-6-oxopyridazin-1-yl]-N-(4-iodophenyl)acetamide |
Molecular weight | 519.339 |
Hydrogen bond acceptor | 5 |
Hydrogen bond donor | 1 |
XlogP | 3.2 |
Synonyms | BDBM50435901 SCHEMBL18015863 |
Inchi Key | COJKOCXBOKKCES-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C22H22IN3O4/c1-14-8-16(9-15-10-19(29-2)12-20(11-15)30-3)22(28)26(25-14)13-21(27)24-18-6-4-17(23)5-7-18/h4-8,10-12H,9,13H2,1-3H3,(H,24,27) |
PubChem CID | 71699065 |
ChEMBL | CHEMBL2391442 |
IUPHAR | N/A |
BindingDB | 50435901 |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand is heavier than 500 daltons. |
Parameter | Value | Reference | Database source |
---|---|---|---|
EC50 | <50000.0 nM | PMID23685570 | BindingDB |
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