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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Neurotensin receptor type 2
Species	Rattus norvegicus (Rat)
Gene	Ntsr2
Synonym	NTRL NTR2 NT2R NT-R-2 neurotensin receptor type 2 levocabastine-sensitive neurotensin receptor High-affinity levocabastine-sensitive neurotensin receptor NTS2 receptor [ Show all ]
Disease	N/A for non-human GPCRs
Length	416
Amino acid sequence	METSSPWPPRPSPSAGLSLEARLGVDTRLWAKVLFTALYSLIFAFGTAGNALSVHVVLKARAGRPGRLRYHVLSLALSALLLLLVSMPMELYNFVWSHYPWVFGDLGCRGYYFVRELCAYATVLSVASLSAERCLAVCQPLRARRLLTPRRTRRLLSLVWVASLGLALPMAVIMGQKHEVESADGEPEPASRVCTVLVSRATLQVFIQVNVLVSFALPLALTAFLNGITVNHLMALYSQVPSASAQVSSIPSRLELLSEEGLLGFITWRKTLSLGVQASLVRHKDASQIRSLQHSAQVLRAIVAVYVICWLPYHARRLMYCYIPDDGWTNELYDFYHYFYMVTNTLFYVSSAVTPILYNAVSSSFRKLFLESLGSLCGEQHSLVPLPQEAPESTTSTYSFRLWGSPRNPSLGEIQV
UniProt	Q63384
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5106
IUPHAR	310
DrugBank	N/A

Ligand

Name	CHEMBL3403504
Molecular formula	C29H31ClN4O4
IUPAC name	(2S)-2-[[1-(7-chloroquinolin-4-yl)-5-(2,6-dimethoxyphenyl)pyrazol-3-yl]methylamino]-2-cyclohexylacetic acid
Molecular weight	535.041
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	3.5
Synonyms	BDBM50069088
Inchi Key	UCPIZCJXHXRCNC-NDEPHWFRSA-N
Inchi ID	InChI=1S/C29H31ClN4O4/c1-37-25-9-6-10-26(38-2)27(25)24-16-20(17-32-28(29(35)36)18-7-4-3-5-8-18)33-34(24)23-13-14-31-22-15-19(30)11-12-21(22)23/h6,9-16,18,28,32H,3-5,7-8,17H2,1-2H3,(H,35,36)/t28-/m0/s1
PubChem CID	118729837
ChEMBL	CHEMBL3403504
IUPHAR	N/A
BindingDB	50069088
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
Ki	<10000.0 nM	PMID25881832	BindingDB,ChEMBL

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