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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Mas-related G-protein coupled receptor member X1
Species	Mus musculus (Mouse)
Gene	Mrgprx1
Synonym	Mas-related G-protein coupled receptor member C11 Sensory neuron-specific G-protein coupled receptor 1
Disease	N/A for non-human GPCRs
Length	322
Amino acid sequence	MDPTISSHDTESTPLNETGHPNCTPILTLSFLVLITTLVGLAGNTIVLWLLGFRMRRKAISVYILNLALADSFFLCCHFIDSLLRIIDFYGLYAHKLSKDILGNAAIIPYISGLSILSAISTERCLCVLWPIWYHCHRPRNMSAIICALIWVLSFLMGILDWFSGFLGETHHHLWKNVDFIITAFLIFLFMLLSGSSLALLLRILCGPRRKPLSRLYVTIALTVMVYLICGLPLGLYLFLLYWFGVHLHYPFCHIYQVTAVLSCVNSSANPIIYFLVGSFRQHRKHRSLKRVLKRALEDTPEEDEYTDSHLHKTTEISESRY
UniProt	Q8CIP3
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3341576
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	Rfamide
Molecular formula	C15H24N6O2
IUPAC name	(2S)-2-amino-N-[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]-5-(diaminomethylideneamino)pentanamide
Molecular weight	320.397
Hydrogen bond acceptor	4
Hydrogen bond donor	5
XlogP	-2.0
Synonyms	AC1L3U57 n5-(diaminomethylidene)-l-ornithyl-l-phenylalaninamide arginylphenylalaninamide SCHEMBL1373212 119051-99-9 H-Arg-Phe-NH2 AC1Q5IPT R-F-NH2 (2S)-2-amino-N-[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]-5-(diaminomethylideneamino)pentanamide ZINC2554967 34388-59-5 L-Phenylalaninamide, L-arginyl- Arg-phe-NH2 (S)-2-amino-N-((S)-1-amino-1-oxo-3-phenylpropan-2-yl)-5-guanidinopentanamide CHEMBL3343990 [ Show all ]
Inchi Key	CQZWLVDDIOZTJI-RYUDHWBXSA-N
Inchi ID	InChI=1S/C15H24N6O2/c16-11(7-4-8-20-15(18)19)14(23)21-12(13(17)22)9-10-5-2-1-3-6-10/h1-3,5-6,11-12H,4,7-9,16H2,(H2,17,22)(H,21,23)(H4,18,19,20)/t11-,12-/m0/s1
PubChem CID	122185
ChEMBL	CHEMBL3343990
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
EC50	501.19 nM	PMID25288495	ChEMBL

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