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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	G-protein coupled receptor 35
Species	Homo sapiens (Human)
Gene	GPR35
Synonym	G-protein coupled receptor 3 GPR35 KYNA receptor Kynurenic acid receptor
Disease	N/A
Length	309
Amino acid sequence	MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKSQDSLCVTLA
UniProt	Q9HC97
Protein Data Bank	N/A
GPCR-HGmod model	Q9HC97
3D structure model	This predicted structure model is from GPCR-EXP Q9HC97.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL1293267
IUPHAR	102
DrugBank	BE0005562

Ligand

Name	3,4-DINITROPHENOL
Molecular formula	C6H4N2O5
IUPAC name	3,4-dinitrophenol
Molecular weight	184.107
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	1.2
Synonyms	KB-28419 ZLD0416 AC1L1X5V BRN 1969398 DB-021953 SCHEMBL213758 4-06-00-01384 (Beilstein Handbook Reference) AKLOLDQYWQAREW-UHFFFAOYSA-N CCRIS 3105 EINECS 209-415-3 ZINC4521448 3,4-Dinitrofenol 8530AB AX8082178 CHEMBL3347427 I01-0816 LS-104568 3,4-Dinitrophenol, moistened with water, >=97.0% (HPLC) ACMC-1AY8J C-07184 DNX TC-169994 577-71-9 AKOS015888235 CHEBI:39358 FCH1118138 zlchem 950 3,4-Dinitrofenol [Czech] A831591 BCP25455 CTK1H3308 I108F156M4 Phenol, 3,4-dinitro- 3,4-DNP AJ-51414 CC-13312 DTXSID80206407 UNII-I108F156M4 3,4-dinitro phenol 6,5-Dinitrophenol AN-46037 FT-0632424 [ Show all ]
Inchi Key	AKLOLDQYWQAREW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C6H4N2O5/c9-4-1-2-5(7(10)11)6(3-4)8(12)13/h1-3,9H
PubChem CID	11348
ChEMBL	CHEMBL3347427
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
EC50	<500000.0 nM	MedChemComm, (2012) 3:10:1270	ChEMBL
EC50	112000.0 nM	MedChemComm, (2012) 3:10:1270	ChEMBL
Efficacy	<6.0 %	MedChemComm, (2012) 3:10:1270	ChEMBL
Efficacy	178.0 pM	MedChemComm, (2012) 3:10:1270	ChEMBL

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