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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Prostaglandin E2 receptor EP3 subtype
Species	Rattus norvegicus (Rat)
Gene	Ptger3
Synonym	EP3 receptor PGE receptor EP3 subtype PGE2 receptor EP3 subtype prostaglandin E receptor 3 prostanoid EP3 receptor
Disease	N/A for non-human GPCRs
Length	365
Amino acid sequence	MAGVWAPEHSVEAHSNQSSAADGCGSVSVAFPITMMVTGFVGNALAMLLVVRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTSPVVILVYLSQRRWEQLDPSGRLCTFFGLTMTVFGLSSLLVASAMAVERALAIRAPHWYASHMKTRATPVLLGVWLSVLAFALLPVLGVGRYSVQWPGTWCFISTGPAGNETDSAREPGSVAFASAFACLGLLALVVTFACNLATIKALVSRCRAKAAASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLIMMLKMIFNQMSVEQCKTQMGKEKECNSFLIAVRLASLNQILDPWVYLLLRKILLRKFCQIRDHTNYASSSTSLPCPGSSVLMWSDQLER
UniProt	P34980
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5674
IUPHAR	342
DrugBank	N/A

Ligand

Name	BDBM50384442
Molecular formula	C18H12N2O4
IUPAC name	4-hydroxy-5-(6-naphthalen-2-yl-2-oxo-1H-pyridin-3-yl)-3H-1,3-oxazol-2-one
Molecular weight	320.304
Hydrogen bond acceptor	4
Hydrogen bond donor	3
XlogP	2.4
Synonyms	N/A
Inchi Key	YTISMEVEPKYCLE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H12N2O4/c21-16-13(15-17(22)20-18(23)24-15)7-8-14(19-16)12-6-5-10-3-1-2-4-11(10)9-12/h1-9,22H,(H,19,21)(H,20,23)
PubChem CID	91929890
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50384442
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	316.23 nM	PMID24900213	BindingDB

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