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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
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GPCR

Name	N-formyl peptide receptor 2
Species	Homo sapiens (Human)
Gene	FPR2
Synonym	FPRH1 FPRH2 FPRL1 HM63 Lipoxin A4 receptor LXA4 receptor LXA4R FPR2A FPR2/ALX Fpr-rs2 ALX ALX/FPR2 ALXR FMLP-R-I FMLP-related receptor I FMLPX formyl peptide receptor 2 formyl peptide receptor, related sequence 2 Formyl peptide receptor-like 1 RFP [ Show all ]
Disease	N/A
Length	351
Amino acid sequence	METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVTTICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNFASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPMLYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
UniProt	P25090
Protein Data Bank	N/A
GPCR-HGmod model	P25090
3D structure model	This predicted structure model is from GPCR-EXP P25090.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4227
IUPHAR	223
DrugBank	N/A

Ligand

Name	MLS000117714
Molecular formula	C19H26N2O5S
IUPAC name	2-[[2-(3-methoxyphenyl)-5-methyl-1,3-oxazol-4-yl]methylsulfonyl]-N-(3-methylbutyl)acetamide
Molecular weight	394.486
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	2.6
Synonyms	2-[[2-(3-methoxyphenyl)-5-methyl-1,3-oxazol-4-yl]methylsulfonyl]-N-(3-methylbutyl)ethanamide cid_5307092 SCHEMBL12008022 AC1NSBTD MCULE-6837008708 2-({[2-(3-methoxyphenyl)-5-methyl-1,3-oxazol-4-yl]methyl}sulfonyl)-N-(3-methylbutyl)acetamide MolPort-007-639-731 2-[[2-(3-methoxyphenyl)-5-methyl-4-oxazolyl]methylsulfonyl]-N-(3-methylbutyl)acetamide HMS2237K09 SMR000094662 AKOS001841793 2-[[2-(3-methoxyphenyl)-5-methyl-1,3-oxazol-4-yl]methylsulfonyl]-N-(3-methylbutyl)acetamide CHEMBL1545295 N-isoamyl-2-[[2-(3-methoxyphenyl)-5-methyl-oxazol-4-yl]methylsulfonyl]acetamide HMS3366L17 ZINC5058436 BDBM37786 MLS002587356 [ Show all ]
Inchi Key	CGNPCWDCNXIDCJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H26N2O5S/c1-13(2)8-9-20-18(22)12-27(23,24)11-17-14(3)26-19(21-17)15-6-5-7-16(10-15)25-4/h5-7,10,13H,8-9,11-12H2,1-4H3,(H,20,22)
PubChem CID	5307092
ChEMBL	CHEMBL1545295
IUPHAR	N/A
BindingDB	37786
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	<66700.0 nM	N/A	BindingDB
Ki	<40300.0 nM	N/A	BindingDB

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