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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Somatostatin receptor type 4
Species	Homo sapiens (Human)
Gene	SSTR4
Synonym	SS4R SS4-R SS-4-R SRIF2B SST4 receptor
Disease	N/A
Length	388
Amino acid sequence	MSAPSTLPPGGEEGLGTAWPSAANASSAPAEAEEAVAGPGDARAAGMVAIQCIYALVCLVGLVGNALVIFVILRYAKMKTATNIYLLNLAVADELFMLSVPFVASSAALRHWPFGSVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLGVWLASLLVTLPIAIFADTRPARGGQAVACNLQWPHPAWSAVFVVYTFLLGFLLPVLAIGLCYLLIVGKMRAVALRAGWQQRRRSEKKITRLVLMVVVVFVLCWMPFYVVQLLNLFVTSLDATVNHVSLILSYANSCANPILYGFLSDNFRRFFQRVLCLRCCLLEGAGGAEEEPLDYYATALKSKGGAGCMCPPLPCQQEALQPEPGRKRIPLTRTTTF
UniProt	P31391
Protein Data Bank	N/A
GPCR-HGmod model	P31391
3D structure model	This predicted structure model is from GPCR-EXP P31391.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL1853
IUPHAR	358
DrugBank	BE0009273

Ligand

Name	CHEMBL1079007
Molecular formula	C22H27N3O2S
IUPAC name	4-N-(1,3-benzothiazol-2-yl)-1-N-(3-ethoxy-4-methoxyphenyl)cyclohexane-1,4-diamine
Molecular weight	397.537
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	6.0
Synonyms	BDBM50311341 N1-(benzo[d]thiazol-2-yl)-N4-(3-ethoxy-4-methoxyphenyl)cyclohexane-1,4-diamine
Inchi Key	AETYXCWWYJOPNZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H27N3O2S/c1-3-27-20-14-17(12-13-19(20)26-2)23-15-8-10-16(11-9-15)24-22-25-18-6-4-5-7-21(18)28-22/h4-7,12-16,23H,3,8-11H2,1-2H3,(H,24,25)
PubChem CID	46882449
ChEMBL	CHEMBL1079007
IUPHAR	N/A
BindingDB	50311341
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Ki	<10000.0 nM	PMID19786348	PDSP,BindingDB,ChEMBL

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