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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Histamine H2 receptor
Species	Cavia porcellus (Guinea pig)
Gene	HRH2
Synonym	Gastric receptor I H2R HH2R
Disease	N/A for non-human GPCRs
Length	359
Amino acid sequence	MAFNGTVPSFCMDFTVYKVTISVILIILILVTVAGNVVVCLAVGLNRRLRSLTNCFIVSLAVTDLLLGLLVLPFSAIYQLSCKWSFSKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVTDPLRYPVLITPARVAISLVFIWVISITLSFLSIHLGWNSRNETSKDNDTIVKCKVQVNEVYGLVDGLVTFYLPLLIMCITYFRIFKIAREQARRINHIGSWKAATIREHKATVTLAAVMGAFIICWFPYFTVFVYRGLKGDDAVNEVFEDVVLWLGYANSALNPILYAALNRDFRTAYHQLFCCRLASHNSHETSLRLNNSQLNRSQCQEPRWQEDKPLNLQVWSGTEVTAPQGATNR
UniProt	P47747
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2882
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	4-Methylburimamide
Molecular formula	C10H18N4S
IUPAC name	1-methyl-3-[4-(5-methyl-1H-imidazol-4-yl)butyl]thiourea
Molecular weight	226.342
Hydrogen bond acceptor	2
Hydrogen bond donor	3
XlogP	0.8
Synonyms	CHEBI:1896 Thiourea, N-methyl-N'-[4-(4-methyl-1H-imidazol-5-yl)butyl]- 1-methyl-3-[4-(5-methyl-1H-imidazol-4-yl)butyl]thiourea DTXSID00199266 AC1MJ3MH SCHEMBL11103342 N-Methyl-N'-(4-(5-methyl-1H-imidazol-4-yl)butyl)thiourea C11801 Thiourea, N-methyl-N'-(4-(5-methyl-1H-imidazol-4-yl)butyl)- CHEMBL3248396 51264-00-7 N-methyl-N'-[4-(5-methyl-4-imidazolyl)-butyl]-thiourea [ Show all ]
Inchi Key	UKUMBWIAJWVEDN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C10H18N4S/c1-8-9(14-7-13-8)5-3-4-6-12-10(15)11-2/h7H,3-6H2,1-2H3,(H,13,14)(H2,11,12,15)
PubChem CID	3084972
ChEMBL	CHEMBL3248396
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Kb	8900.0 nM	PMID17751	ChEMBL

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