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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Prostaglandin E2 receptor EP3 subtype
Species	Rattus norvegicus (Rat)
Gene	Ptger3
Synonym	EP3 receptor PGE receptor EP3 subtype PGE2 receptor EP3 subtype prostaglandin E receptor 3 prostanoid EP3 receptor
Disease	N/A for non-human GPCRs
Length	365
Amino acid sequence	MAGVWAPEHSVEAHSNQSSAADGCGSVSVAFPITMMVTGFVGNALAMLLVVRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTSPVVILVYLSQRRWEQLDPSGRLCTFFGLTMTVFGLSSLLVASAMAVERALAIRAPHWYASHMKTRATPVLLGVWLSVLAFALLPVLGVGRYSVQWPGTWCFISTGPAGNETDSAREPGSVAFASAFACLGLLALVVTFACNLATIKALVSRCRAKAAASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLIMMLKMIFNQMSVEQCKTQMGKEKECNSFLIAVRLASLNQILDPWVYLLLRKILLRKFCQIRDHTNYASSSTSLPCPGSSVLMWSDQLER
UniProt	P34980
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5674
IUPHAR	342
DrugBank	N/A

Ligand

Name	CHEMBL2035508
Molecular formula	C20H19N3O4
IUPAC name	5-[6-(1-methylindol-5-yl)-2-oxo-1H-pyridin-3-yl]-5-propan-2-yl-1,3-oxazolidine-2,4-dione
Molecular weight	365.389
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	2.4
Synonyms	BDBM50384445
Inchi Key	UFGZUAACSOMAKB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H19N3O4/c1-11(2)20(18(25)22-19(26)27-20)14-5-6-15(21-17(14)24)12-4-7-16-13(10-12)8-9-23(16)3/h4-11H,1-3H3,(H,21,24)(H,22,25,26)
PubChem CID	49850347
ChEMBL	CHEMBL2035508
IUPHAR	N/A
BindingDB	50384445
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	7.94 nM	PMID24900213	BindingDB
Ki	7.943 nM	PMID24900213	ChEMBL

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