You can:
Name | Succinate receptor 1 |
---|---|
Species | Homo sapiens (Human) |
Gene | SUCNR1 |
Synonym | succinate receptor 1 succinate receptor P2Y purinoceptor 1-like P2Y purinoceptor 1 GPR91 [ Show all ] |
Disease | N/A |
Length | 334 |
Amino acid sequence | MLGIMAWNATCKNWLAAEAALEKYYLSIFYGIEFVVGVLGNTIVVYGYIFSLKNWNSSNIYLFNLSVSDLAFLCTLPMLIRSYANGNWIYGDVLCISNRYVLHANLYTSILFLTFISIDRYLIIKYPFREHLLQKKEFAILISLAIWVLVTLELLPILPLINPVITDNGTTCNDFASSGDPNYNLIYSMCLTLLGFLIPLFVMCFFYYKIALFLKQRNRQVATALPLEKPLNLVIMAVVIFSVLFTPYHVMRNVRIASRLGSWKQYQCTQVVINSFYIVTRPLAFLNSVINPVFYFLLGDHFRDMLMNQLRHNFKSLTSFSRWAHELLLSFREK |
UniProt | Q9BXA5 |
Protein Data Bank | N/A |
GPCR-HGmod model | Q9BXA5 |
3D structure model | This predicted structure model is from GPCR-EXP Q9BXA5. |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL2150838 |
IUPHAR | 166 |
DrugBank | BE0002258 |
Name | CHEMBL2153580 |
---|---|
Molecular formula | C22H18ClFN4O2 |
IUPAC name | N-[[3-(3-chloro-4-fluorophenyl)-1,2-oxazol-5-yl]methyl]-4-(1,8-naphthyridin-2-yl)butanamide |
Molecular weight | 424.86 |
Hydrogen bond acceptor | 6 |
Hydrogen bond donor | 1 |
XlogP | 3.7 |
Synonyms | BDBM50393142 |
Inchi Key | SGJQNINMCWELAW-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C22H18ClFN4O2/c23-18-11-15(7-9-19(18)24)20-12-17(30-28-20)13-26-21(29)5-1-4-16-8-6-14-3-2-10-25-22(14)27-16/h2-3,6-12H,1,4-5,13H2,(H,26,29) |
PubChem CID | 71453138 |
ChEMBL | CHEMBL2153580 |
IUPHAR | N/A |
BindingDB | 50393142 |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand satisfies Lipinski's rule of five. |
Parameter | Value | Reference | Database source |
---|---|---|---|
IC50 | 90.0 nM | PMID21571530 | BindingDB,ChEMBL |
zhanglabzhanggroup.org | +65-6601-1241 | Computing 1, 13 Computing Drive, Singapore 117417