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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Muscarinic acetylcholine receptor M1
Species	Rattus norvegicus (Rat)
Gene	Chrm1
Synonym	cholinergic receptor, muscarinic 1 cholinergic receptor, muscarinic 1, CNS cholinergic receptor M1 muscarinic acetylcholine receptor M1 receptor M1R Chrm-1 [ Show all ]
Disease	N/A for non-human GPCRs
Length	460
Amino acid sequence	MNTSVPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSSSERSQPGAEGSPESPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDSEAQAPTKQPPKSSPNTVKRPTKKGRDRGGKGQKPRGKEQLAKRKTFSLVKEKKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTVNPMCYALCNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
UniProt	P08482
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL276
IUPHAR	13
DrugBank	N/A

Ligand

Name	RS-86
Molecular formula	C11H19BrN2O2
IUPAC name	2-ethyl-8-methyl-2,8-diazaspiro[4.5]decane-1,3-dione;hydrobromide
Molecular weight	291.189
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	None
Synonyms	2-Nitrophenyl ?-D-galactopyranoside RS-86 hydrobromide 2,8-Diazaspiro(4,5)decane-1,3-dione, 2-ethyl-8-methyl-, hydrobromide 5ASV6M91QU D05HKB 2-ethyl-8-methyl-2,8-diazaspiro[4,5]decane-1,3-dione hydrobromide AC1Q23N4 RS 86, hydrobromide 2-Nitrophenyl \|A-D-galactopyranoside CHEMBL542883 TR-031003 2,8-Diazaspiro(4.5)decane-1,3-dione, 2-ethyl-8-methyl-, hydrobromide (1:1) 7524-74-5 LS-59967 2-ethyl-8-methyl-2,8-diazaspiro[4.5]decane-1,3-dione hydrobromide(1:1) C11H18N2O2.HBr 19105-63-6 3-ethyl-8-methyl-3,8-diazaspiro[4.5]decane-2,4-dione hydrobromide CTK8D5439 UNII-5ASV6M91QU 2-Ethyl-8-methyl-2,8-diazaspiro(4,5)decane-1,3-dione hydrobromide AC1L3EP8 RS 86 [ Show all ]
Inchi Key	RKVCNLSYEWDGNX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C11H18N2O2.BrH/c1-3-13-9(14)8-11(10(13)15)4-6-12(2)7-5-11;/h3-8H2,1-2H3;1H
PubChem CID	87933
ChEMBL	CHEMBL542883
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	Partition coefficient log P of this ligand is not available.

Experimental Data

Parameter	Value	Reference	Database source
Ki	460.0 nM	PMID8360873	ChEMBL

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