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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Muscarinic acetylcholine receptor M1
Species	Rattus norvegicus (Rat)
Gene	Chrm1
Synonym	cholinergic receptor, muscarinic 1 cholinergic receptor, muscarinic 1, CNS cholinergic receptor M1 muscarinic acetylcholine receptor M1 receptor M1R Chrm-1 [ Show all ]
Disease	N/A for non-human GPCRs
Length	460
Amino acid sequence	MNTSVPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSSSERSQPGAEGSPESPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDSEAQAPTKQPPKSSPNTVKRPTKKGRDRGGKGQKPRGKEQLAKRKTFSLVKEKKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTVNPMCYALCNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
UniProt	P08482
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL276
IUPHAR	13
DrugBank	N/A

Ligand

Name	CHEMBL129886
Molecular formula	C9H14N4
IUPAC name	1-methyl-5-(2-methyltriazol-4-yl)-3,6-dihydro-2H-pyridine
Molecular weight	178.239
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	0.5
Synonyms	BOOLVSGWJUFBES-UHFFFAOYSA-N SCHEMBL8402584 1-Methyl-5-(2-methyl-2H-[1,2,3]triazol-4-yl)-1,2,3,6-tetrahydro-pyridine 2-Methyl-4-(1-methyl-1,2,5,6-tetrahydro-3-pyridyl)-1,2,3-triazole BDBM50038219 2-Methyl-4-[(1-methyl-1,2,3,6-tetrahydropyridin)-5-yl]-2H-1,2,3-triazole [ Show all ]
Inchi Key	BOOLVSGWJUFBES-UHFFFAOYSA-N
Inchi ID	InChI=1S/C9H14N4/c1-12-5-3-4-8(7-12)9-6-10-13(2)11-9/h4,6H,3,5,7H2,1-2H3
PubChem CID	10442260
ChEMBL	CHEMBL129886
IUPHAR	N/A
BindingDB	50038219
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
EC50	430.0 nM	PMID7990109	ChEMBL
Ki	35.0 nM	PMID7990109	BindingDB,ChEMBL

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