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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Cholecystokinin receptor type A
Species	Cavia porcellus (Guinea pig)
Gene	CCKAR
Synonym	CCK-A receptor CCK-AR CCK1-R Cholecystokinin-1 receptor
Disease	N/A for non-human GPCRs
Length	430
Amino acid sequence	MDVVDSLFVNGSNITSACELGFENETLFCLDRPRPSKEWQPAVQILLYSLIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPSLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICKPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTKNNNQTGNMCRFLLPNDVMQQTWHTFLLLILFLIPGIVMMVAYGLISLELYQGIKFDAIQKKSAKERKTSTGSSGPMEDSDGCYLQKSRHPRKLELRQLSPSSSGSNRINRIRSSSSTANLMAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAERHLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGTPGVRGEMGEEEEGRTTGASLSRYSYSHMSTSAPPP
UniProt	Q63931
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3501
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL325161
Molecular formula	C31H28N4O4
IUPAC name	ethyl (2R)-2-[[(2R)-3-(1H-indol-3-yl)-2-(quinoline-3-carbonylamino)propanoyl]amino]-2-phenylacetate
Molecular weight	520.589
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	4.9
Synonyms	BDBM50008630 {3-(1H-Indol-3-yl)-2-[(quinoline-3-carbonyl)-amino]-propionylamino}-phenyl-acetic acid ethyl ester (R)-2-[(R)-3-(1H-Indol-3-yl)-2-(3-quinolinylcarbonylamino)propanoylamino]-2-phenylacetic acid ethyl ester
Inchi Key	BNTFCCSMRNSBKQ-VSGBNLITSA-N
Inchi ID	InChI=1S/C31H28N4O4/c1-2-39-31(38)28(20-10-4-3-5-11-20)35-30(37)27(17-22-18-33-26-15-9-7-13-24(22)26)34-29(36)23-16-21-12-6-8-14-25(21)32-19-23/h3-16,18-19,27-28,33H,2,17H2,1H3,(H,34,36)(H,35,37)/t27-,28-/m1/s1
PubChem CID	15104632
ChEMBL	CHEMBL325161
IUPHAR	N/A
BindingDB	50008630
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
IC50	165.0 nM	PMID1766000	BindingDB,ChEMBL

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