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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Mu-type opioid receptor
Species	Mus musculus (Mouse)
Gene	Oprm1
Synonym	opioid receptor, mu 1 opioid receptor OP3 Mu receptor MOR-1 MOPr MOP M-OR-1 [ Show all ]
Disease	N/A for non-human GPCRs
Length	398
Amino acid sequence	MDSSAGPGNISDCSDPLAPASCSPAPGSWLNLSHVDGNQSDPCGPNRTGLGGSHSLCPQTGSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGNILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQQNSARIRQNTREHPSTANTVDRTNHQLENLEAETAPLP
UniProt	P42866
Protein Data Bank	4dkl, 5c1m, 6dde, 6ddf
GPCR-HGmod model	N/A
3D structure model	This structure is from PDB ID 4dkl.
BioLiP	BL0416752, BL0416751, BL0321492, BL0224753, BL0224754, BL0224755,BL0224756, BL0321491
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2858
IUPHAR	319
DrugBank	N/A

Ligand

Name	CHEMBL434542
Molecular formula	C30H36N2O2
IUPAC name	4-[(3-acetylphenyl)-[8-(3-methylbut-3-enyl)-8-azabicyclo[3.2.1]octan-3-ylidene]methyl]-N-ethylbenzamide
Molecular weight	456.63
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	6.1
Synonyms	4-{(3-Acetyl-phenyl)-[8-(3-methyl-but-3-enyl)-8-aza-bicyclo[3.2.1]oct-3-ylidene]-methyl}-N-ethyl-benzamide BDBM50155103
Inchi Key	BNEJMAVUXISIQN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C30H36N2O2/c1-5-31-30(34)23-11-9-22(10-12-23)29(25-8-6-7-24(17-25)21(4)33)26-18-27-13-14-28(19-26)32(27)16-15-20(2)3/h6-12,17,27-28H,2,5,13-16,18-19H2,1,3-4H3,(H,31,34)
PubChem CID	44395612
ChEMBL	CHEMBL434542
IUPHAR	N/A
BindingDB	50155103
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Ki	1.9 nM	PMID15482911	BindingDB,ChEMBL
Ratio	1.1 -	PMID15482911	ChEMBL

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