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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	N-formyl peptide receptor 3
Species	Homo sapiens (Human)
Gene	FPR3
Synonym	FMLP-related receptor II Lxa4r LXA4-R FPRL2 Fprl1 FMLP-R-II FPR3 Formyl peptide receptor-like 2 FMLPY FPRH1 [ Show all ]
Disease	N/A
Length	353
Amino acid sequence	METNFSIPLNETEEVLPEPAGHTVLWIFSLLVHGVTFVFGVLGNGLVIWVAGFRMTRTVNTICYLNLALADFSFSAILPFRMVSVAMREKWPFGSFLCKLVHVMIDINLFVSVYLITIIALDRCICVLHPAWAQNHRTMSLAKRVMTGLWIFTIVLTLPNFIFWTTISTTNGDTYCIFNFAFWGDTAVERLNVFITMAKVFLILHFIIGFSVPMSIITVCYGIIAAKIHRNHMIKSSRPLRVFAAVVASFFICWFPYELIGILMAVWLKEMLLNGKYKIILVLINPTSSLAFFNSCLNPILYVFMGRNFQERLIRSLPTSLERALTEVPDSAQTSNTDTTSASPPEETELQAM
UniProt	P25089
Protein Data Bank	N/A
GPCR-HGmod model	P25089
3D structure model	This predicted structure model is from GPCR-EXP P25089.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	N/A
IUPHAR	224
DrugBank	N/A

Ligand

Name	CHEMBL2391441
Molecular formula	C21H17BrN4O2
IUPAC name	N-(4-bromophenyl)-2-[5-[(4-cyanophenyl)methyl]-3-methyl-6-oxopyridazin-1-yl]acetamide
Molecular weight	437.297
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	3.0
Synonyms	BDBM50435902 SCHEMBL18015871
Inchi Key	QFFAMOWJLHRYFH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H17BrN4O2/c1-14-10-17(11-15-2-4-16(12-23)5-3-15)21(28)26(25-14)13-20(27)24-19-8-6-18(22)7-9-19/h2-10H,11,13H2,1H3,(H,24,27)
PubChem CID	71699064
ChEMBL	CHEMBL2391441
IUPHAR	N/A
BindingDB	50435902
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
EC50	<50000.0 nM	PMID23685570	BindingDB

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