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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Melanin-concentrating hormone receptor 1
Species	Mus musculus (Mouse)
Gene	Mchr1
Synonym	SLC-1 {ECO:0000303\|PubMed:11159839} MCHR-1 MCHR MCH1R MCH1 receptor MCH-R1 MCH-1R MCH receptor 1 GPR24 G-protein coupled receptor 24 G protein-coupled receptor 24 somatostatin receptor-like protein [ Show all ]
Disease	N/A for non-human GPCRs
Length	353
Amino acid sequence	MDLQASLLSTGPNASNISDGQDNFTLAGPPPRTRSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMAIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT
UniProt	Q8JZL2
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4730
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL374843
Molecular formula	C28H33ClF2N4O
IUPAC name	3-(3-chloro-4-fluorophenyl)-1-[(3R,6S)-6-(3-cyanophenyl)-3-bicyclo[4.1.0]heptanyl]-1-[2-[2-fluoroethyl(propan-2-yl)amino]ethyl]urea
Molecular weight	515.046
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	6.0
Synonyms	SCHEMBL14266155 3-(3-chloro-4-fluorophenyl)-1-((3R,6S)-6-(3-cyanophenyl)bicyclo[4.1.0]heptan-3-yl)-1-(2-((2-fluoroethyl)(isopropyl)amino)ethyl)urea BDBM50215589
Inchi Key	PSLHRUILNLJKQN-FKCQOYNMSA-N
Inchi ID	InChI=1S/C28H33ClF2N4O/c1-19(2)34(11-10-30)12-13-35(27(36)33-23-6-7-26(31)25(29)16-23)24-8-9-28(17-22(28)15-24)21-5-3-4-20(14-21)18-32/h3-7,14,16,19,22,24H,8-13,15,17H2,1-2H3,(H,33,36)/t22?,24-,28-/m1/s1
PubChem CID	44424211
ChEMBL	CHEMBL374843
IUPHAR	N/A
BindingDB	50215589
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Activity	66.0 %	PMID17572094	ChEMBL
Activity	81.0 %	PMID17572094	ChEMBL

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