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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	N-formyl peptide receptor 3
Species	Homo sapiens (Human)
Gene	FPR3
Synonym	FMLP-related receptor II Lxa4r LXA4-R FPRL2 Fprl1 FMLP-R-II FPR3 Formyl peptide receptor-like 2 FMLPY FPRH1 [ Show all ]
Disease	N/A
Length	353
Amino acid sequence	METNFSIPLNETEEVLPEPAGHTVLWIFSLLVHGVTFVFGVLGNGLVIWVAGFRMTRTVNTICYLNLALADFSFSAILPFRMVSVAMREKWPFGSFLCKLVHVMIDINLFVSVYLITIIALDRCICVLHPAWAQNHRTMSLAKRVMTGLWIFTIVLTLPNFIFWTTISTTNGDTYCIFNFAFWGDTAVERLNVFITMAKVFLILHFIIGFSVPMSIITVCYGIIAAKIHRNHMIKSSRPLRVFAAVVASFFICWFPYELIGILMAVWLKEMLLNGKYKIILVLINPTSSLAFFNSCLNPILYVFMGRNFQERLIRSLPTSLERALTEVPDSAQTSNTDTTSASPPEETELQAM
UniProt	P25089
Protein Data Bank	N/A
GPCR-HGmod model	P25089
3D structure model	This predicted structure model is from GPCR-EXP P25089.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	N/A
IUPHAR	224
DrugBank	N/A

Ligand

Name	CHEMBL2391443
Molecular formula	C20H17ClIN3O2
IUPAC name	2-[5-[(3-chlorophenyl)methyl]-3-methyl-6-oxopyridazin-1-yl]-N-(4-iodophenyl)acetamide
Molecular weight	493.729
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	3.9
Synonyms	BDBM50435900 SCHEMBL18015879
Inchi Key	PSLAZNCKJKOLBS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H17ClIN3O2/c1-13-9-15(10-14-3-2-4-16(21)11-14)20(27)25(24-13)12-19(26)23-18-7-5-17(22)6-8-18/h2-9,11H,10,12H2,1H3,(H,23,26)
PubChem CID	71699139
ChEMBL	CHEMBL2391443
IUPHAR	N/A
BindingDB	50435900
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
EC50	<50000.0 nM	PMID23685570	BindingDB

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