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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	N-formyl peptide receptor 2
Species	Homo sapiens (Human)
Gene	FPR2
Synonym	FPRH1 FPRH2 FPRL1 HM63 Lipoxin A4 receptor LXA4 receptor LXA4R FPR2A FPR2/ALX Fpr-rs2 ALX ALX/FPR2 ALXR FMLP-R-I FMLP-related receptor I FMLPX formyl peptide receptor 2 formyl peptide receptor, related sequence 2 Formyl peptide receptor-like 1 RFP [ Show all ]
Disease	N/A
Length	351
Amino acid sequence	METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVTTICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNFASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPMLYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
UniProt	P25090
Protein Data Bank	N/A
GPCR-HGmod model	P25090
3D structure model	This predicted structure model is from GPCR-EXP P25090.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4227
IUPHAR	223
DrugBank	N/A

Ligand

Name	MLS000047151
Molecular formula	C11H10N2O4S2
IUPAC name	methyl 1-(2,1,3-benzothiadiazol-4-ylsulfonyl)cyclopropane-1-carboxylate
Molecular weight	298.331
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	1.3
Synonyms	methyl 1-(2,1,3-benzothiadiazol-4-ylsulfonyl)cyclopropane-1-carboxylate SMR000033162 1-(2,1,3-benzothiadiazol-4-ylsulfonyl)-1-cyclopropanecarboxylic acid methyl ester EU-0032777 AC1MMTR6 methyl 1-(2,1,3-benzothiadiazol-4-ylsulfonyl)cyclopropanecarboxylate CHEMBL1456551 1-piazthiol-4-ylsulfonylcyclopropanecarboxylic acid methyl ester HMS2278L19 BDBM37742 cid_3244290 [ Show all ]
Inchi Key	BJRKOTLNYXDXHI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C11H10N2O4S2/c1-17-10(14)11(5-6-11)19(15,16)8-4-2-3-7-9(8)13-18-12-7/h2-4H,5-6H2,1H3
PubChem CID	3244290
ChEMBL	CHEMBL1456551
IUPHAR	N/A
BindingDB	37742
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	<66700.0 nM	N/A	BindingDB
Ki	<40300.0 nM	N/A	BindingDB

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