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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Growth hormone-releasing hormone receptor
Species	Rattus norvegicus (Rat)
Gene	Ghrhr
Synonym	Ghrfr GHRH receptor GRF receptor GRFR Growth hormone-releasing factor receptor
Disease	N/A for non-human GPCRs
Length	464
Amino acid sequence	MDSLLWATWVLCLLNLWGVALGHLHLECDFITQLRDDELACLQAAEGTNNSSMGCPGTWDGLLCWPPTGSGQWVSLPCPEFFSHFGSDPGAVKRDCTITGWSDPFPPYPVACPVPLELLTEEKSYFSTVKIIYTTGHSISIVALCVAIAILVALRRLHCPRNYIHTQLFATFILKASAVFLKDAAVFQGDSTDHCSMSTILCKVSVAVSHFATMTNFSWLLAEAVYLSCLLASTSPRSKPAFWWLVLAGWGLPVLCTGTWVGCKLAFEDTACWDLDDSSPYWWIIKGPIVLSVGVNFGLFLNIICILLRKLGPAQGGLHTRAQYCNYLLPWSCPLPQVPRERTDLGPSSHEITVQESGTRNCQLPWRLSKSTLLLIPLFGIHYIIFNFLPDSAGLGIRLPLELGLGSFQGFVVAVLYCFLNQEVRTEISRKWYGHDPELLPARRTCTEWTTPPRSRVKVLTSEC
UniProt	Q02644
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3709
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL558422
Molecular formula	C30H36N4O4
IUPAC name	2-[(1S)-1'-[(2R)-2-[(2-amino-2-methylpropanoyl)amino]-3-(1H-indol-3-yl)propanoyl]spiro[1,2-dihydroindene-3,4'-piperidine]-1-yl]acetic acid
Molecular weight	516.642
Hydrogen bond acceptor	5
Hydrogen bond donor	4
XlogP	0.7
Synonyms	BDBM50403632 SCHEMBL2577068 CHEMBL1196866
Inchi Key	NADZKIPHPAUMCV-KBMIEXCESA-N
Inchi ID	InChI=1S/C30H36N4O4/c1-29(2,31)28(38)33-25(15-20-18-32-24-10-6-4-8-22(20)24)27(37)34-13-11-30(12-14-34)17-19(16-26(35)36)21-7-3-5-9-23(21)30/h3-10,18-19,25,32H,11-17,31H2,1-2H3,(H,33,38)(H,35,36)/t19-,25-/m1/s1
PubChem CID	22867262
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50403632
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
EC50	5.8 nM	N/A	BindingDB

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