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Name | D(1A) dopamine receptor |
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Species | Rattus norvegicus (Rat) |
Gene | Drd1 |
Synonym | D1 receptor D1A DADR dopamine D1 receptor Dopamine-1A receptor [ Show all ] |
Disease | N/A for non-human GPCRs |
Length | 446 |
Amino acid sequence | MAPNTSTMDEAGLPAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPLGPFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFTSLEDTEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKNCQTTAGNGNPVECAQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCGSEETQPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFQKAFSTLLGCYRLCPTTNNAIETVSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIAKPLEKLSPALSVILDYDTDVSLEKIQPVTHSGQHST |
UniProt | P18901 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL265 |
IUPHAR | 214 |
DrugBank | N/A |
Name | CHEMBL543964 |
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Molecular formula | C16H16ClN3O |
IUPAC name | 1-(1-methylindol-5-yl)-3-phenylurea;hydrochloride |
Molecular weight | 301.774 |
Hydrogen bond acceptor | 1 |
Hydrogen bond donor | 3 |
XlogP | None |
Synonyms | N/A |
Inchi Key | BEJJGNCQRGGHES-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C16H15N3O.ClH/c1-19-10-9-12-11-14(7-8-15(12)19)18-16(20)17-13-5-3-2-4-6-13;/h2-11H,1H3,(H2,17,18,20);1H |
PubChem CID | 45259292 |
ChEMBL | CHEMBL543964 |
IUPHAR | N/A |
BindingDB | N/A |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | Partition coefficient log P of this ligand is not available. |
Parameter | Value | Reference | Database source |
---|---|---|---|
pK1 | >5.0 - | PMID8478907 | ChEMBL |
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