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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	5-hydroxytryptamine receptor 2C
Species	Rattus norvegicus (Rat)
Gene	Htr2c
Synonym	5-HT-1C serotonin 1c receptor HTR1C 5-hydroxytryptamine receptor 1C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 5-HTR2C 5-HT2C receptor 5-HT2C 5-HT1C 5-HT-2C serotonin receptor 2C [ Show all ]
Disease	N/A for non-human GPCRs
Length	460
Amino acid sequence	MVNLGNAVRSLLMHLIGLLVWQFDISISPVAAIVTDTFNSSDGGRLFQFPDGVQNWPALSIVVIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVWPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWAISIGVSVPIPVIGLRDESKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYFLTIYVLRRQTLMLLRGHTEEELANMSLNFLNCCCKKNGGEEENAPNPNPDQKPRRKKKEKRPRGTMQAINNEKKASKVLGIVFFVFLIMWCPFFITNILSVLCGKACNQKLMEKLLNVFVWIGYVCSGINPLVYTLFNKIYRRAFSKYLRCDYKPDKKPPVRQIPRVAATALSGRELNVNIYRHTNERVARKANDPEPGIEMQVENLELPVNPSNVVSERISSV
UniProt	P08909
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL324
IUPHAR	8
DrugBank	BE0004882

Ligand

Name	CHEMBL543964
Molecular formula	C16H16ClN3O
IUPAC name	1-(1-methylindol-5-yl)-3-phenylurea;hydrochloride
Molecular weight	301.774
Hydrogen bond acceptor	1
Hydrogen bond donor	3
XlogP	None
Synonyms	N/A
Inchi Key	BEJJGNCQRGGHES-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H15N3O.ClH/c1-19-10-9-12-11-14(7-8-15(12)19)18-16(20)17-13-5-3-2-4-6-13;/h2-11H,1H3,(H2,17,18,20);1H
PubChem CID	45259292
ChEMBL	CHEMBL543964
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	Partition coefficient log P of this ligand is not available.

Experimental Data

Parameter	Value	Reference	Database source
pK1	6.86 -	PMID8478907	ChEMBL

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