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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Alpha-2B adrenergic receptor
Species	Didelphis virginiana (North American opossum)
Gene	ADRA2B
Synonym	Alpha-2B adrenoceptor Alpha-2B adrenoreceptor Alpha-2BAR
Disease	N/A for non-human GPCRs
Length	382
Amino acid sequence	AIAAVITFLILFTIFGNALVILAVLTSRSLRAPQNLFLVSLAAADILVATLIIPFSLANELLGYWYFRHTWCEVYLALDVLFCTSSIVHLCAISLDRYWSVSRALEYNSKRTPRRIKGIILTVWLIAAFISLPPLIYKGDKGKKPGGRPQCKLNEEAWYILSSSIGSFFAPCLIMILVYLRIYLIAKRRNRQGPHGKQAPGDGDTGPSALGGTSTISKLPPSILPAVGEANGHSKPPGEREGGEQMGDPTSPSTPPNQSSVGPEDGSQKQEEEEEEEEEEEEECGPPAPPTSSSLQGTPNFQPSQGSQVLATLRGQVLLARGPASLGLQPWRRRTQMNREKRFTFVLAVVIGVFVLCWFPFFFSYSLGAICPQHCKVPHGLF
UniProt	O77715
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	N/A
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	SK&F-104078
Molecular formula	C16H22ClNO
IUPAC name	6-chloro-3-methyl-9-(3-methylbut-2-enoxy)-1,2,4,5-tetrahydro-3-benzazepine
Molecular weight	279.808
Hydrogen bond acceptor	2
Hydrogen bond donor	0
XlogP	4.4
Synonyms	22XBK6DY1E CHEBI:125603 PDSP2_000607 UNII-22XBK6DY1E 6-chloro-3-methyl-9-(3-methylbut-2-enoxy)-1,2,4,5-tetrahydro-3-benzazepine CTK4A7072 1H-3-Benzazepine, 6-chloro-2,3,4,5-tetrahydro-3-methyl-9-((3-methyl-2-butenyl)oxy)- BDBM50030623 LS-172138 SKF-104078 SCHEMBL8091302 AC1L3UBS D08OWQ SK-104078 1H-3-Benzazepine,6-chloro-2,3,4,5-tetrahydro-3-methyl-9-[(3-methyl-2-buten-1-yl)oxy]- BRD-K62103095-001-01-6 PDSP1_000610 skf104078 6-Chloro-3-methyl-9-(3-methyl-but-2-enyloxy)-2,3,4,5-tetrahydro-1H-benzo[d]azepine CHEMBL114166 SK&F 104078 110857-22-2 ACMC-20mdr0 DTXSID40149402 Skf 104078 [ Show all ]
Inchi Key	MBYSTKNEMJZSIK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H22ClNO/c1-12(2)8-11-19-16-5-4-15(17)13-6-9-18(3)10-7-14(13)16/h4-5,8H,6-7,9-11H2,1-3H3
PubChem CID	122295
ChEMBL	CHEMBL114166
IUPHAR	N/A
BindingDB	50030623
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	42.65 nM	PMID7908054	BindingDB
Ki	54.95 nM	PMID7908054	BindingDB

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