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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Glucose-dependent insulinotropic receptor
Species	Mus musculus (Mouse)
Gene	Gpr119
Synonym	G protein-coupled receptor 119 G-protein coupled receptor 119 G-protein coupled receptor 2 glucose-dependent insulinotropic receptor GPCR2 GPR119 [ Show all ]
Disease	N/A for non-human GPCRs
Length	335
Amino acid sequence	MESSFSFGVILAVLTILIIAVNALVVVAMLLSIYKNDGVGLCFTLNLAVADTLIGVAISGLVTDQLSSSAQHTQKTLCSLRMAFVTSSAAASVLTVMLIAFDRYLAIKQPLRYFQIMNGLVAGACIAGLWLVSYLIGFLPLGVSIFQQTTYHGPCSFFAVFHPRFVLTLSCAGFFPAVLLFVFFYCDMLKIASVHSQQIRKMEHAGAMAGAYRPPRSVNDFKAVRTIAVLIGSFTLSWSPFLITSIVQVACHKCCLYQVLEKYLWLLGVGNSLLNPLIYAYWQREVRQQLYHMALGVKKFFTSILLLLPARNRGPERTRESAYHIVTISHPELDG
UniProt	Q7TQP3
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5263
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL2058406
Molecular formula	C21H31N3O3
IUPAC name	tert-butyl 4-[3-[(3-oxo-1,2-dihydroisoindol-5-yl)amino]propyl]piperidine-1-carboxylate
Molecular weight	373.497
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	3.1
Synonyms	BDBM50387905
Inchi Key	LFTBMVKQYIOACD-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H31N3O3/c1-21(2,3)27-20(26)24-11-8-15(9-12-24)5-4-10-22-17-7-6-16-14-23-19(25)18(16)13-17/h6-7,13,15,22H,4-5,8-12,14H2,1-3H3,(H,23,25)
PubChem CID	62706692
ChEMBL	CHEMBL2058406
IUPHAR	N/A
BindingDB	50387905
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
EC50	892.0 nM	PMID22765901	BindingDB,ChEMBL
Emax	97.0 %	PMID22765901	ChEMBL

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