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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Sphingosine 1-phosphate receptor 2
Species	Homo sapiens (Human)
Gene	S1PR2
Synonym	Endothelial differentiation G-protein coupled receptor 5 Sphingosine 1-phosphate receptor Edg-5 S1P2 receptor S1P2 S1P receptor Edg-5 S1P receptor 2 edg5 endothelial differentiation G protein-coupled receptor 5 GPCR18 Gpcr13 G protein-coupled receptor 13 [ Show all ]
Disease	Hypertension
Length	353
Amino acid sequence	MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV
UniProt	O95136
Protein Data Bank	N/A
GPCR-HGmod model	O95136
3D structure model	This predicted structure model is from GPCR-EXP O95136.
BioLiP	N/A
Therapeutic Target Database	T47888
ChEMBL	CHEMBL2955
IUPHAR	276
DrugBank	N/A

Ligand

Name	BAS 09529732
Molecular formula	C16H17N3O3
IUPAC name	1-(5-phenyl-1,2-oxazole-3-carbonyl)piperidine-4-carboxamide
Molecular weight	299.33
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	1.2
Synonyms	ZINC815054 CHEMBL1565208 1-[(5-phenylisoxazol-3-yl)carbonyl]piperidine-4-carboxamide MolPort-001-604-588 SR-01000367787-2 1-(5-phenyl-1,2-oxazole-3-carbonyl)piperidine-4-carboxamide HMS1694G02 AC1LM099 SR-01000367787 ST063306 1-(5-Phenyl-isoxazole-3-carbonyl)-piperidine-4-carboxylic acid amide MCULE-1560154433 SR-01000367787-1 AKOS000559747 [ Show all ]
Inchi Key	AZIDAIPMLWSEPN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H17N3O3/c17-15(20)12-6-8-19(9-7-12)16(21)13-10-14(22-18-13)11-4-2-1-3-5-11/h1-5,10,12H,6-9H2,(H2,17,20)
PubChem CID	1093757
ChEMBL	CHEMBL1565208
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
EC50	<10000.0 nM	PubChem BioAssay data set	ChEMBL

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