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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	G-protein coupled receptor 35
Species	Homo sapiens (Human)
Gene	GPR35
Synonym	G-protein coupled receptor 3 GPR35 KYNA receptor Kynurenic acid receptor
Disease	N/A
Length	309
Amino acid sequence	MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKSQDSLCVTLA
UniProt	Q9HC97
Protein Data Bank	N/A
GPCR-HGmod model	Q9HC97
3D structure model	This predicted structure model is from GPCR-EXP Q9HC97.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL1293267
IUPHAR	102
DrugBank	BE0005562

Ligand

Name	CHEMBL1914591
Molecular formula	C20H29BrO2S2
IUPAC name	3-bromo-6-tridecylthieno[3,2-b]thiophene-5-carboxylic acid
Molecular weight	445.474
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	10.0
Synonyms	SCHEMBL404495 6-bromo-3-tridecyl-thieno[3,2-b]thiophene-2-carboxylic acid 3-Tridecyl-6-bromo-thieno[3,2-b]thiophene-2-carboxylic acid AYKNFAXHCPLUOW-UHFFFAOYSA-N BDBM50357189
Inchi Key	AYKNFAXHCPLUOW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H29BrO2S2/c1-2-3-4-5-6-7-8-9-10-11-12-13-15-17-19(16(21)14-24-17)25-18(15)20(22)23/h14H,2-13H2,1H3,(H,22,23)
PubChem CID	53258796
ChEMBL	CHEMBL1914591
IUPHAR	N/A
BindingDB	50357189
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Activity	77.0 %	PMID21950657	ChEMBL
EC50	2310.0 nM	PMID21950657	BindingDB,ChEMBL
IC50	1870.0 nM	PMID21950657	BindingDB,ChEMBL

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