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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Somatostatin receptor type 1
Species	Rattus norvegicus (Rat)
Gene	Sstr1
Synonym	SRIF-2 SS-1-R SS1-R SS1R SST1 receptor
Disease	N/A for non-human GPCRs
Length	391
Amino acid sequence	MFPNGTAPSPTSSPSSSPGGCGEGVCSRGPGSGAADGMEEPGRNSSQNGTLSEGQGSAILISFIYSVVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADELLMLSVPFLVTSTLLRHWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLGVWVLSLLVILPIVVFSRTAANSDGTVACNMLMPEPAQRWLVGFVLYTFLMGFLLPVGAICLCYVLIIAKMRMVALKAGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQLVNVFAEQDDATVSQLSVILGYANSCANPILYGFLSDNFKRSFQRILCLSWMDNAAEEPVDYYATALKSRAYSVEDFQPENLESGGVFRNGTCASRISTL
UniProt	P28646
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4652
IUPHAR	355
DrugBank	N/A

Ligand

Name	CHEMBL250305
Molecular formula	C27H31N5O4
IUPAC name	2-[4-[(3R,4aR,10aR)-6-methoxy-1-methyl-3,4,4a,5,10,10a-hexahydro-2H-benzo[g]quinoline-3-carbonyl]piperazin-1-yl]-5-nitrobenzonitrile
Molecular weight	489.576
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	3.3
Synonyms	BDBM50423351
Inchi Key	KPXPZPCOBCPHSK-DZRGJMJISA-N
Inchi ID	InChI=1S/C27H31N5O4/c1-29-17-21(12-19-14-23-18(15-25(19)29)4-3-5-26(23)36-2)27(33)31-10-8-30(9-11-31)24-7-6-22(32(34)35)13-20(24)16-28/h3-7,13,19,21,25H,8-12,14-15,17H2,1-2H3/t19-,21-,25-/m1/s1
PubChem CID	44441917
ChEMBL	CHEMBL250305
IUPHAR	N/A
BindingDB	50423351
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Kd	3.2 nM	PMID17512199	BindingDB
Kd	3.236 nM	PMID17512199	ChEMBL

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