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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	5-hydroxytryptamine receptor 1D
Species	Mus musculus (Mouse)
Gene	Htr1d
Synonym	HTRL Htr1db HT1DA Gpcr14 5-HT-1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled 5-HT1Dalpha 5-HT1D receptor 5-HT1D serotonin receptor 1D [ Show all ]
Disease	N/A for non-human GPCRs
Length	374
Amino acid sequence	MSPPNQSLEGLPQEASNRSLNVTGAWDPEVLQALRISLVVVLSVITLATVLSNAFVLTTILLTKKLHTPANYLIGSLATTDLLVSILVMPISIAYTTTRTWNFGQILCDIWVSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAAVWIISICISIPPLFWRQATAHEEMSDCLVNTSQISYTIYSTCGAFYIPSILLIILYGRIYVAARSRILNPPSLYGKRFTTAQLITGSAGSSLCSLNPSLHESHTHTVGSPLFFNQVKIKLADSILERKRISAARERKATKTLGIILGAFIICWLPFFVVSLVLPICRDSCWIHPALFDFFTWLGYLNSLINPVIYTVFNEDFRQAFQKVVHFRKIS
UniProt	Q61224
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4297
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL98433
Molecular formula	C20H20ClNO4
IUPAC name	N-[(3R,4S)-6-acetyl-3-hydroxy-2,2-dimethyl-3,4-dihydrochromen-4-yl]-2-chlorobenzamide
Molecular weight	373.833
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	2.8
Synonyms	SCHEMBL8335761 BDBM50217231 N-[[(3R,4S)-3,4-Dihydro-2,2-dimethyl-3-hydroxy-6-acetyl-2H-1-benzopyran]-4-yl]-2-chlorobenzamide
Inchi Key	KMBXNPJEKNKOQQ-ZWKOTPCHSA-N
Inchi ID	InChI=1S/C20H20ClNO4/c1-11(23)12-8-9-16-14(10-12)17(18(24)20(2,3)26-16)22-19(25)13-6-4-5-7-15(13)21/h4-10,17-18,24H,1-3H3,(H,22,25)/t17-,18+/m0/s1
PubChem CID	10547383
ChEMBL	CHEMBL98433
IUPHAR	N/A
BindingDB	50217231
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Increase	140.0 %	PMID10021946	ChEMBL
Increase	478.0 %	PMID10021946	ChEMBL

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